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Inhibition of Histone Deacetylases 1 and 6 Enhances Cytarabine-Induced Apoptosis in Pediatric Acute Myeloid Leukemia Cells

BACKGROUND: Pediatric acute myeloid leukemia (AML) remains a challenging disease to treat even with intensified cytarabine-based chemotherapy. Histone deacetylases (HDACs) have been reported to be promising therapeutic targets for treating AML. However, HDAC family members that are involved in chemo...

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Bibliografski detalji
Glavni autori: Xu, Xuelian, Xie, Chengzhi, Edwards, Holly, Zhou, Hui, Buck, Steven A., Ge, Yubin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040224/
https://ncbi.nlm.nih.gov/pubmed/21359182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017138
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