Class I and Class II Histone Deacetylases Are Potential Therapeutic Targets for Treating Pancreatic Cancer

BACKGROUND: Pancreatic cancer is a highly malignant disease with an extremely poor prognosis. Histone deacetylase inhibitors (HDACIs) have shown promising antitumor activities against preclinical models of pancreatic cancer, either alone or in combination with chemotherapeutic agents. In this study,...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Guan, He, Jing, Zhao, Jianyun, Yun, Wenting, Xie, Chengzhi, Taub, Jeffrey W., Azmi, Asfar, Mohammad, Ramzi M., Dong, Yan, Kong, Wei, Guo, Yingjie, Ge, Yubin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522644/
https://ncbi.nlm.nih.gov/pubmed/23251689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052095
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