Aminosugar-based immunomodulator lipid A: synthetic approaches

Autor Zamyatina, Alla
Vydáno v Beilstein J Org Chem (2018)

Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways

Autor Zamyatina, Alla, Heine, Holger
Vydáno v Front Immunol (2020)

Corrigendum: Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways

Autor Zamyatina, Alla, Heine, Holger
Vydáno v Front Immunol (2021)

Synthesis of Zwitterionic 1,1′-Glycosylphosphodiester: A Partial Structure of Galactosamine-Modified Francisella Lipid A

Autor Baum, David, Kosma, Paul, Zamyatina, Alla
Vydáno 2014

Stereoselective Synthesis of α- and β-l-Ara4N Glycosyl H-Phosphonates and a Neoglycoconjugate Comprising Glycosyl Phosphodiester Linked β-l-Ara4N

Autor Hollaus, Ralph, Kosma, Paul, Zamyatina, Alla
Vydáno v Org Lett (2016)

Synthesis of Lipid A and Inner Core LPS ligands containing 4-amino-4-deoxy-l-arabinose units

Autor Zamyatina, Alla, Hollaus, Ralph, Blaukopf, Markus, Kosma, Paul
Vydáno 2011

Crystal and molecular structure of methyl l-glycero-α-d-manno-heptopyranoside, and synthesis of 1→7 linked l-glycero-d-manno-heptobiose and its methyl α-glycoside

Autor Artner, Daniel, Stanetty, Christian, Mereiter, Kurt, Zamyatina, Alla, Kosma, Paul
Vydáno 2011

Efficient Synthesis of 4-Amino-4-deoxy-L-arabinose and Spacer-equipped 4-Amino-4-deoxy-L-arabinopyranosides by Transglycosylation Reactions

Autor Müller, Bernhard, Blaukopf, Markus, Hofinger, Andreas, Zamyatina, Alla, Brade, Helmut, Kosma, Paul
Vydáno 2010

Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics

Autor Adanitsch, Florian, Shi, Jianjin, Shao, Feng, Beyaert, Rudi, Heine, Holger, Zamyatina, Alla
Vydáno v Chem Sci (2018)

Chemical Synthesis of Burkholderia Lipid A Modified with Glycosyl Phosphodiester-Linked 4-Amino-4-deoxy-β-l-arabinose and Its Immunomodulatory Potential

Autor Hollaus, Ralph, Ittig, Simon, Hofinger, Andreas, Haegman, Mira, Beyaert, Rudi, Kosma, Paul, Zamyatina, Alla
Vydáno v Chemistry (2015)

Biosynthesis Pathway of ADP-l-glycero-β-d-manno-Heptose in Escherichia coli

Autor Kneidinger, Bernd, Marolda, Cristina, Graninger, Michael, Zamyatina, Alla, McArthur, Fiona, Kosma, Paul, Valvano, Miguel A., Messner, Paul
Vydáno 2002

Development of αGlcN(1↔1)αMan-Based Lipid A Mimetics as a Novel Class of Potent Toll-like Receptor 4 Agonists

Autor Adanitsch, Florian, Ittig, Simon, Stöckl, Johannes, Oblak, Alja, Haegman, Mira, Jerala, Roman, Beyaert, Rudi, Kosma, Paul, Zamyatina, Alla
Vydáno 2014

Shortening the Lipid A Acyl Chains of Bordetella pertussis Enables Depletion of Lipopolysaccharide Endotoxic Activity

Autor Arenas, Jesús, Pupo, Elder, Phielix, Coen, David, Dionne, Zariri, Afshin, Zamyatina, Alla, Tommassen, Jan, van der Ley, Peter
Vydáno v Vaccines (Basel) (2020)

ADP‐heptose is a newly identified pathogen‐associated molecular pattern of Shigella flexneri

Autor García‐Weber, Diego, Dangeard, Anne‐Sophie, Cornil, Johan, Thai, Linda, Rytter, Héloïse, Zamyatina, Alla, Mulard, Laurence A, Arrieumerlou, Cécile
Vydáno v EMBO Rep (2018)

Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics

Autor Heine, Holger, Adanitsch, Florian, Peternelj, Tina Tinkara, Haegman, Mira, Kasper, Christoph, Ittig, Simon, Beyaert, Rudi, Jerala, Roman, Zamyatina, Alla
Vydáno v Front Immunol (2021)

A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family

Autor Yao, Qing, Lu, Qiuhe, Wan, Xiaobo, Song, Feng, Xu, Yue, Hu, Mo, Zamyatina, Alla, Liu, Xiaoyun, Huang, Niu, Zhu, Ping, Shao, Feng
Vydáno v eLife (2014)

Conformationally Constrained Lipid A Mimetics for Exploration of Structural Basis of TLR4/MD-2 Activation by Lipopolysaccharide

Autor Artner, Daniel, Oblak, Alja, Ittig, Simon, Garate, Jose Antonio, Horvat, Simon, Arrieumerlou, Cécile, Hofinger, Andreas, Oostenbrink, Chris, Jerala, Roman, Kosma, Paul, Zamyatina, Alla
Vydáno 2013

Anti-endotoxic activity and structural basis for human MD-2·TLR4 antagonism of tetraacylated lipid A mimetics based on βGlcN(1↔1)αGlcN scaffold

Autor Garate, Jose Antonio, Stöckl, Johannes, del Carmen Fernández-Alonso, María, Artner, Daniel, Haegman, Mira, Oostenbrink, Chris, Jiménez-Barbero, Jesús, Beyaert, Rudi, Heine, Holger, Kosma, Paul, Zamyatina, Alla
Vydáno v Innate Immun (2015)

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation

Autor Schijns, Virgil, Majhen, Dragomira, van der Ley, Peter, Thakur, Aneesh, Summerfield, Artur, Berisio, Rita, Nativi, Cristina, Fernández-Tejada, Alberto, Alvarez-Dominguez, Carmen, Gizurarson, Sveinbjörn, Zamyatina, Alla, Molinaro, Antonio, Rosano, Camillo, Jakopin, Žiga, Gursel, Ihsan, McClean, Siobhán
Vydáno v Pharmaceutics (2021)