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Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways

The innate immune response to lipopolysaccharide is essential for host defense against Gram-negative bacteria. In response to bacterial infection, the TLR4/MD-2 complex that is expressed on the surface of macrophages, monocytes, dendritic, and epithelial cells senses picomolar concentrations of endo...

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Pubblicato in:Front Immunol
Autori principali: Zamyatina, Alla, Heine, Holger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732686/
https://ncbi.nlm.nih.gov/pubmed/33329561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585146
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