A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family

A large group of bacterial virulence autotransporters including AIDA-I from diffusely adhering E. coli (DAEC) and TibA from enterotoxigenic E. coli (ETEC) require hyperglycosylation for functioning. Here we demonstrate that TibC from ETEC harbors a heptosyltransferase activity on TibA and AIDA-I, de...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Yao, Qing, Lu, Qiuhe, Wan, Xiaobo, Song, Feng, Xu, Yue, Hu, Mo, Zamyatina, Alla, Liu, Xiaoyun, Huang, Niu, Zhu, Ping, Shao, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358343/
https://ncbi.nlm.nih.gov/pubmed/25310236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03714
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