Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis

Targeting eukaryotic proteins for deamidation modification is increasingly appreciated as a general bacterial virulence mechanism. Here, we present an atomic view of how a bacterial deamidase effector, cycle-inhibiting factor homolog in Burkholderia pseudomallei (CHBP), recognizes its host targets,...

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Detalhes bibliográficos
Main Authors: Yao, Qing, Cui, Jixin, Wang, Jiayi, Li, Ting, Wan, Xiaobo, Luo, Tianming, Gong, Yi-Nan, Xu, Ying, Huang, Niu, Shao, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528514/
https://ncbi.nlm.nih.gov/pubmed/23175788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210831109
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