Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human iPSCs

Por Srikanth, Priya, Young-Pearse, Tracy L.
Publicado no J Neurogenet (2014)

Modeling developmental neuropsychiatric disorders with iPSC technology: Challenges and opportunities

Por Young-Pearse, Tracy L., Morrow, Eric M.
Publicado no Curr Opin Neurobiol (2015)

Induced pluripotent stem cells as a discovery tool for Alzheimer's disease

Por Sullivan, Sarah E., Young-Pearse, Tracy L.
Publicado no Brain Res (2015)

In utero electroporation as a tool for genetic manipulation in vivo in order to study psychiatric disorders: from genes to circuits and behaviors

Por Taniguchi, Yu, Young-Pearse, Tracy, Sawa, Akira, Kamiya, Atsushi
Publicado em 2011

Systematic evaluation of candidate ligands regulating ectodomain shedding of Amyloid Precursor Protein

Por Rice, Heather C., Young-Pearse, Tracy L., Selkoe, Dennis J.
Publicado em 2013

In utero Electroporation followed by Primary Neuronal Culture for Studying Gene Function in Subset of Cortical Neurons

Por Rice, Heather, Suth, Seiyam, Cavanaugh, William, Bai, Jilin, Young-Pearse, Tracy L.
Publicado em 2010

Comparison and Optimization of hiPSC Forebrain Cortical Differentiation Protocols

Por Muratore, Christina R., Srikanth, Priya, Callahan, Dana G., Young-Pearse, Tracy L.
Publicado em 2014

Biochemical and Functional Interaction of Disrupted-in-Schizophrenia 1 and Amyloid Precursor Protein Regulates Neuronal Migration during Mammalian Cortical Development

Por Young-Pearse, Tracy L., Suth, Seiyam, Luth, Eric S., Sawa, Akira, Selkoe, Dennis J.
Publicado em 2010

Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1

Por Young-Pearse, Tracy L, Chen, Allen C, Chang, Rui, Marquez, Cesar, Selkoe, Dennis J
Publicado em 2008

Soluble APP functions as a vascular niche signal that controls adult neural stem cell number

Por Sato, Yuya, Uchida, Yutaka, Hu, Jingqiong, Young-Pearse, Tracy L., Niikura, Takako, Mukouyama, Yoh-suke
Publicado no Development (2017)

Pancortins interact with amyloid precursor protein and modulate cortical cell migration

Por Rice, Heather C., Townsend, Matthew, Bai, Jilin, Suth, Seiyam, Cavanaugh, William, Selkoe, Dennis J., Young-Pearse, Tracy L.
Publicado em 2012

APC is an RNA-Binding Protein and its Interactome Provides a Link to Neural Development and Microtubule Assembly

Por Preitner, Nicolas, Quan, Jie, Nowakowski, Dan W., Hancock, Melissa L., Shi, Jianhua, Tcherkezian, Joseph, Young-Pearse, Tracy L., Flanagan, John G.
Publicado em 2014

Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes

Por Liao, Mei-Chen, Muratore, Christina R., Gierahn, Todd M., Sullivan, Sarah E., Srikanth, Priya, De Jager, Philip L., Love, J. Christopher, Young-Pearse, Tracy L.
Publicado no J Neurosci (2016)

The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

Por Muratore, Christina R., Rice, Heather C., Srikanth, Priya, Callahan, Dana G., Shin, Taehwan, Benjamin, Lawrence N. P., Walsh, Dominic M., Selkoe, Dennis J., Young-Pearse, Tracy L.
Publicado em 2014

Genomic DISC1 disruption in hiPSCs alters Wnt signaling and neural cell fate

Por Srikanth, Priya, Han, Karam, Callahan, Dana G., Makovkina, Eugenia, Muratore, Christina R., Lalli, Matthew A., Zhou, Honglin, Boyd, Justin D., Kosik, Kenneth S., Selkoe, Dennis J., Young-Pearse, Tracy L.
Publicado no Cell Rep (2015)

Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP

Por Wang, Zemin, Jackson, Rosemary J., Hong, Wei, Taylor, Walter M., Corbett, Grant T., Moreno, Arturo, Liu, Wen, Li, Shaomin, Frosch, Matthew P., Slutsky, Inna, Young-Pearse, Tracy L., Spires-Jones, Tara L., Walsh, Dominic M.
Publicado no J Neurosci (2017)