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Soluble APP functions as a vascular niche signal that controls adult neural stem cell number

The molecular mechanism by which NSC number is controlled in the neurogenic regions of the adult brain is not fully understood but it has been shown that vascular niche signals regulate neural stem cell (NSC) quiescence and growth. Here, we have uncovered a role for soluble amyloid precursor protein...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Sato, Yuya, Uchida, Yutaka, Hu, Jingqiong, Young-Pearse, Tracy L., Niikura, Takako, Mukouyama, Yoh-suke
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560038/
https://ncbi.nlm.nih.gov/pubmed/28694255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143370
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