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Soluble APP functions as a vascular niche signal that controls adult neural stem cell number

The molecular mechanism by which NSC number is controlled in the neurogenic regions of the adult brain is not fully understood but it has been shown that vascular niche signals regulate neural stem cell (NSC) quiescence and growth. Here, we have uncovered a role for soluble amyloid precursor protein...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Sato, Yuya, Uchida, Yutaka, Hu, Jingqiong, Young-Pearse, Tracy L., Niikura, Takako, Mukouyama, Yoh-suke
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560038/
https://ncbi.nlm.nih.gov/pubmed/28694255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143370
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