Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state

Tekijä Afik, Shaked, Yates, Kathleen B., Bi, Kevin, Darko, Samuel, Godec, Jernej, Gerdemann, Ulrike, Swadling, Leo, Douek, Daniel C., Klenerman, Paul, Barnes, Eleanor J., Sharpe, Arlene H., Haining, W. Nicholas, Yosef, Nir
Julkaisussa Nucleic Acids Res (2017)

Immediate Dysfunction of Vaccine-Elicited CD8(+) T Cells Primed in the Absence of CD4(+) T Cells

Tekijä Provine, Nicholas M., Larocca, Rafael A., Aid, Malika, Penaloza-MacMaster, Pablo, Badamchi-Zadeh, Alexander, Borducchi, Erica N., Yates, Kathleen B., Abbink, Peter, Kirilova, Marinela, Ng’ang’a, David, Bramson, Jonathan, Haining, W. Nicholas, Barouch, Dan H.
Julkaisussa J Immunol (2016)

Maintenance of CD4 T cell fitness through regulation of Foxo1

Tekijä Newton, Ryan H., Shrestha, Sharad, Sullivan, Jenna M., Yates, Kathleen B., Compeer, Ewoud B., Ron-Harel, Noga, Blazar, Bruce R., Bensinger, Steven J., Haining, W. Nicholas, Dustin, Michael L., Campbell, Daniel J., Chi, Hongbo, Turka, Laurence A.
Julkaisussa Nat Immunol (2018)

A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system

Tekijä LaFleur, Martin W., Nguyen, Thao H., Coxe, Matthew A., Yates, Kathleen B., Trombley, Justin D., Weiss, Sarah A., Brown, Flavian D., Gillis, Jacob E., Coxe, Daniel J., Doench, John G., Haining, W. Nicholas, Sharpe, Arlene H.
Julkaisussa Nat Commun (2019)

PTPN2 regulates the generation of exhausted CD8(+) T cell subpopulations and restrains tumor immunity

Tekijä LaFleur, Martin W., Nguyen, Thao H., Coxe, Matthew A., Miller, Brian C., Yates, Kathleen B., Gillis, Jacob E., Sen, Debattama R., Gaudiano, Emily F., Abosy, Rose Al, Freeman, Gordon J., Haining, W. Nicholas, Sharpe, Arlene H.
Julkaisussa Nat Immunol (2019)

Vaccine-Elicited CD4 T Cells Induce Immunopathology Following Chronic LCMV Infection

Tekijä Penaloza-MacMaster, Pablo, Barber, Daniel L., Wherry, E. John, Provine, Nicholas M., Teigler, Jeffrey E., Parenteau, Lily, Blackmore, Stephen, Borducchi, Erica N., Larocca, Rafael A., Yates, Kathleen B., Shen, Hao, Haining, W. Nicholas, Sommerstein, Rami, Pinschewer, Daniel D., Ahmed, Rafi, Barouch, Dan. H.
Julkaisussa Science (2015)

The PD-1 Pathway Regulates Development and Function of Memory CD8(+) T Cells following Respiratory Viral Infection

Tekijä Pauken, Kristen E., Godec, Jernej, Odorizzi, Pamela M., Brown, Keturah E., Yates, Kathleen B., Ngiow, Shin Foong, Burke, Kelly P., Maleri, Seth, Grande, Shannon M., Francisco, Loise M., Ali, Mohammed-Alkhatim, Imam, Sabrina, Freeman, Gordon J., Haining, W. Nicholas, Wherry, E. John, Sharpe, Arlene H.
Julkaisussa Cell Rep (2020)

The epigenetic landscape of T cell exhaustion

Tekijä Sen, Debattama R., Kaminski, James, Barnitz, R. Anthony, Kurachi, Makoto, Gerdemann, Ulrike, Yates, Kathleen B., Tsao, Hsiao-Wei, Godec, Jernej, LaFleur, Martin W., Brown, Flavian D., Tonnerre, Pierre, Chung, Raymond T., Tully, Damien C., Allen, Todd M., Frahm, Nicole, Lauer, Georg M., Wherry, E. John, Yosef, Nir, Haining, W. Nicholas
Julkaisussa Science (2016)

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

Tekijä Manguso, Robert T., Pope, Hans W., Zimmer, Margaret D., Brown, Flavian D., Yates, Kathleen B., Miller, Brian C., Collins, Natalie B., Bi, Kevin, LaFleur, Martin W., Juneja, Vikram R., Weiss, Sarah A., Lo, Jennifer, Fisher, David E., Miao, Diana, Van Allen, Eliezer, Root, David E., Sharpe, Arlene H., Doench, John G., Haining, W. Nicholas
Julkaisussa Nature (2017)

Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling

Tekijä Brown, Flavian D., Sen, Debattama R., LaFleur, Martin W., Godec, Jernej, Lukacs-Kornek, Veronika, Schildberg, Frank A., Kim, Hye-Jung, Yates, Kathleen B., Ricoult, Stéphane J. H., Bi, Kevin, Trombley, Justin D., Kapoor, Varun N., Stanley, Illana A., Cremasco, Viviana, Danial, Nika N., Manning, Brendan D., Sharpe, Arlene H., Haining, W. Nicholas, Turley, Shannon J.
Julkaisussa Nat Immunol (2019)

Subsets of exhausted CD8(+) T cells differentially mediate tumor control and respond to checkpoint blockade

Tekijä Miller, Brian C., Sen, Debattama R., Abosy, Rose Al, Bi, Kevin, Virkud, Yamini V., LaFleur, Martin W., Yates, Kathleen B., Lako, Ana, Felt, Kristen, Naik, Girish S., Manos, Michael, Gjini, Evisa, Kuchroo, Juhi R., Ishizuka, Jeffrey J., Collier, Jenna L., Griffin, Gabriel K., Maleri, Seth, Comstock, Dawn E., Weiss, Sarah A., Brown, Flavian D., Panda, Arpit, Zimmer, Margaret D., Manguso, Robert T., Hodi, F. Stephen, Rodig, Scott J., Sharpe, Arlene H., Haining, W. Nicholas
Julkaisussa Nat Immunol (2019)

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

Tekijä Ishizuka, Jeffrey J., Manguso, Robert T., Cheruiyot, Collins K., Bi, Kevin, Panda, Arpit, Vellve, Arvin Iracheta, Miller, Brian C., Du, Peter P., Yates, Kathleen B., Dubrot, Juan, Buchumenski, Ilana, Comstock, Dawn E., Brown, Flavian D., Ayer, Austin, Kohnle, Ian C., Pope, Hans W., Zimmer, Margaret D., Sen, Debattama R., Lane-Reticker, Sarah K., Robitschek, Emily J., Griffin, Gabriel K., Collins, Natalie B., Long, Adrienne H., Doench, John G., Kozono, David, Levanon, Erez Y., Haining, W. Nicholas
Julkaisussa Nature (2018)

Author Correction: Subsets of exhausted CD8(+) T cells differentially mediate tumor control and respond to checkpoint blockade

Tekijä Miller, Brian C., Sen, Debattama R., Abosy, Rose Al, Bi, Kevin, Virkud, Yamini V., LaFleur, Martin W., Yates, Kathleen B., Lako, Ana, Felt, Kristen, Naik, Girish S., Manos, Michael, Gjini, Evisa, Kuchroo, Juhi R., Ishizuka, Jeffrey J., Collier, Jenna L., Griffin, Gabriel K., Maleri, Seth, Comstock, Dawn E., Weiss, Sarah A., Brown, Flavian D., Panda, Arpit, Zimmer, Margaret D., Manguso, Robert T., Hodi, F. Stephen, Rodig, Scott J., Sharpe, Arlene H., Haining, W. Nicholas
Julkaisussa Nat Immunol (2019)