Probing the Secrets of Alzheimer’s Disease Using Human-induced Pluripotent Stem Cell Technology

av Goldstein, Lawrence S. B., Reyna, Sol, Woodruff, Grace
I publikationen Neurotherapeutics (2014)

NIR-mbc94, a Fluorescent Ligand that Binds to Endogenous CB(2) Receptors and Is Amenable to High-Throughput Screening

av Sexton, Michelle, Woodruff, Grace, Horne, Eric A., Lin, Yi Hsing, Muccioli, Giulio G., Bai, Mingfeng, Stern, Eric, Bornhop, Darryl J., Stella, Nephi
Publicerad 2011

Defective Transcytosis of APP and Lipoproteins in human iPSC-derived neurons with Familial Alzheimer’s Disease Mutations

av Woodruff, Grace, Reyna, Sol M., Dunlap, Mariah, Van Der Kant, Rik, Callender, Julia A., Young, Jessica E., Roberts, Elizabeth A., Goldstein, Lawrence S. B.
I publikationen Cell Rep (2016)

The Presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells

av Woodruff, Grace, Young, Jessica E., Martinez, Fernando J., Buen, Floyd, Gore, Athurva, Kinaga, Jennifer, Li, Zhe, Yuan, Shauna H., Zhang, Kun, Goldstein, Lawrence S. B.
Publicerad 2013

Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids

av Woodruff, Grace, Phillips, Naomi, Carromeu, Cassiano, Guicherit, Oivin, White, Alistair, Johnson, McCay, Zanella, Fabian, Anson, Blake, Lovenberg, Timothy, Bonaventure, Pascal, Harrington, Anthony W.
I publikationen PLoS One (2020)

Binding of NIR-conPK and NIR-6T to Astrocytomas and Microglial Cells: Evidence for a Protein Related to TSPO

av Sexton, Michelle, Woodruff, Grace, Cudaback, Eiron, Kreitzer, Faith R., Xu, Cong, Lin, Yi Hsing, Möller, Thomas, Bai, Mingfeng, Manning, H. Charles, Bornhop, Darryl, Stella, Nephi
Publicerad 2009

Long-Distance Axonal Growth from Human Induced Pluripotent Stem Cells After Spinal Cord Injury

av Lu, Paul, Woodruff, Grace, Wang, Yaozhi, Graham, Lori, Hunt, Matt, Wu, Di, Boehle, Eileen, Ahmad, Ruhel, Poplawski, Gunnar, Brock, John, Goldstein, Lawrence S. B., Tuszynski, Mark H.
Publicerad 2014

Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes

av Fong, Lauren K., Yang, Max M., dos Santos Chaves, Rodrigo, Reyna, Sol M., Langness, Vanessa F., Woodruff, Grace, Roberts, Elizabeth A., Young, Jessica E., Goldstein, Lawrence S. B.
I publikationen J Biol Chem (2018)

Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells

av Young, Jessica E., Boulanger-Weill, Jonathan, Williams, Daniel A., Woodruff, Grace, Buen, Floyd, Revilla, Arra C., Herrera, Cheryl, Israel, Mason A., Yuan, Shauna H., Edland, Steven D., Goldstein, Lawrence S.B.
I publikationen Cell Stem Cell (2015)

Effect of Potent γ-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1–Induced Pluripotent Stem Cell Mutant Carriers

av Liu, Qing, Waltz, Shannon, Woodruff, Grace, Ouyang, Joe, Israel, Mason A., Herrera, Cheryl, Sarsoza, Floyd, Tanzi, Rudolph E., Koo, Edward H., Ringman, John M., Goldstein, Lawrence S. B., Wagner, Steven L., Yuan, Shauna H.
I publikationen JAMA Neurol (2014)

High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells

av D'Antonio, Matteo, Woodruff, Grace, Nathanson, Jason L., D'Antonio-Chronowska, Agnieszka, Arias, Angelo, Matsui, Hiroko, Williams, Roy, Herrera, Cheryl, Reyna, Sol M., Yeo, Gene W., Goldstein, Lawrence S.B., Panopoulos, Athanasia D., Frazer, Kelly A.
I publikationen Stem Cell Reports (2017)

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

av Marrs, William R, Blankman, Jacqueline L, Horne, Eric A, Thomazeau, Aurore, Lin, Yi Hsing, Coy, Jonathan, Bodor, Agnes L, Muccioli, Giulio G, Hu, Sherry Shu-Jung, Woodruff, Grace, Fung, Susan, Lafourcade, Mathieu, Alexander, Jessica P, Long, Jonathan Z, Li, Weiwei, Xu, Cong, Möller, Thomas, Mackie, Ken, Manzoni, Olivier J, Cravatt, Benjamin F, Stella, Nephi
Publicerad 2010

Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells

av Almenar-Queralt, Angels, Merkurjev, Daria, Kim, Hong Sook, Navarro, Michael, Ma, Qi, Chaves, Rodrigo S., Allegue, Catarina, Driscoll, Shawn P., Chen, Andrew G., Kohlnhofer, Bridget, Fong, Lauren K., Woodruff, Grace, Mackintosh, Carlos, Bohaciakova, Dasa, Hruska-Plochan, Marian, Tadokoro, Takahiro, Young, Jessica E., El Hajj, Nady, Dittrich, Marcus, Marsala, Martin, Goldstein, Lawrence S.B., Garcia-Bassets, Ivan
I publikationen Nat Genet (2019)