Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroids

Human induced Pluripotent Stem Cells (iPSCs) are a powerful tool to dissect the biology of complex human cell types such as those of the central nervous system (CNS). However, robust, high-throughput platforms for reliably measuring activity in human iPSC-derived neuronal cultures are lacking. Here,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Woodruff, Grace, Phillips, Naomi, Carromeu, Cassiano, Guicherit, Oivin, White, Alistair, Johnson, McCay, Zanella, Fabian, Anson, Blake, Lovenberg, Timothy, Bonaventure, Pascal, Harrington, Anthony W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581002/
https://ncbi.nlm.nih.gov/pubmed/33091047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240991
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