Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D Cultures

Neurological disorders affect millions of people worldwide and appear to be on the rise. Whereas the reason for this increase remains unknown, environmental factors are a suspected contributor. Hence, there is an urgent need to develop more complex, biologically relevant, and predictive in vitro ass...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Sirenko, Oksana, Parham, Frederick, Dea, Steven, Sodhi, Neha, Biesmans, Steven, Mora-Castilla, Sergio, Ryan, Kristen, Behl, Mamta, Chandy, Grischa, Crittenden, Carole, Vargas-Hurlston, Sarah, Guicherit, Oivin, Gordon, Ryan, Zanella, Fabian, Carromeu, Cassiano
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
NTP NEUROTOXICOLOGY SCREENING STRATEGIES INITIATIVE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317428/
https://ncbi.nlm.nih.gov/pubmed/30169818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy218
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