NIR-mbc94, a Fluorescent Ligand that Binds to Endogenous CB(2) Receptors and Is Amenable to High-Throughput Screening

High-throughput screening (HTS) of chemical libraries is often used for the unbiased identification of compounds interacting with G protein-coupled receptors (GPCRs), the largest family of therapeutic targets. However, current HTS methods require removing GPCRs from their native environment, which m...

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Autores principales: Sexton, Michelle, Woodruff, Grace, Horne, Eric A., Lin, Yi Hsing, Muccioli, Giulio G., Bai, Mingfeng, Stern, Eric, Bornhop, Darryl J., Stella, Nephi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420821/
https://ncbi.nlm.nih.gov/pubmed/21609837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.02.016
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