Effect of Potent γ-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1–Induced Pluripotent Stem Cell Mutant Carriers

IMPORTANCE: Although considerable effort has been expended developing drug candidates for Alzheimer disease, none have yet succeeded owing to the lack of efficacy or to safety concerns. One potential shortcoming of current approaches to Alzheimer disease drug discovery and development is that they r...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:JAMA Neurol
Main Authors: Liu, Qing, Waltz, Shannon, Woodruff, Grace, Ouyang, Joe, Israel, Mason A., Herrera, Cheryl, Sarsoza, Floyd, Tanzi, Rudolph E., Koo, Edward H., Ringman, John M., Goldstein, Lawrence S. B., Wagner, Steven L., Yuan, Shauna H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374637/
https://ncbi.nlm.nih.gov/pubmed/25285942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.2482
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker