Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP

Por Cary, Stephen P. L., Winger, Jonathan A., Marletta, Michael A.
Publicado em 2005

The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)

Por Winger, Jonathan A, Hantschel, Oliver, Superti-Furga, Giulio, Kuriyan, John
Publicado em 2009

The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase

Por Winger, Jonathan A, Derbyshire, Emily R, Lamers, Meindert H, Marletta, Michael A, Kuriyan, John
Publicado em 2008

TMIC-15. OMX IS A TUMOR MICROENVIRONMENT MODIFIER THAT RESTORES ANTI-TUMOR IMMUNITY AND IMPROVES ANTI-TUMOR EFFICACY BY REDUCING TUMOR HYPOXIA IN INTRACRANIAL GLIOBLASTOMA MOUSE MO...

Por Le Moan, Natacha, Davis, Tina, Leung, Philberta, Ng, Sarah, Winger, Jonathan, Cary, Stephen, Butowski, Nicholas, Krtolica, Ana
Publicado no Neuro Oncol (2018)

Identification of Inhibitors of the Association of ZAP-70 with the T-Cell Receptor by High-Throughput Screen

Por Visperas, Patrick R., Wilson, Christopher G., Winger, Jonathan A., Yan, Qingrong, Lin, Kevin, Arkin, Michelle R., Weiss, Arthur, Kuriyan, John
Publicado no SLAS Discov (2016)

ET-31 RADIOSENSITIZATION BY OMX-4.80P, A PEGylated H-NOX OXYGEN CARRIER THAT PENETRATES AND OXYGENATES HYPOXIC TUMORS, IN PRECLINICAL MODELS OF GLIOBLASTOMA AND OTHER HYPOXIC CANCE...

Por Krtolica, Ana, Le Moan, Natacha, Getz, Jen, Davis, Tina, Ng, Sarah, Bedard, Catherine, Davis, Andrew, Leung, Philberta, Serwer, Laura, Tanaka, Kevin, Keating, Tim, Yan, Feng, Winger, Jonathan, Cary, Stephen
Publicado em 2014

ET-32 HYPOXIA REDUCTION IN INTRACRANIAL GLIOBLASTOMA MODELS BY OMX-4.80P, A PEGylated ENGINEERED H-NOX OXYGEN CARRIER THAT IS LONG-LASTING IN CIRCULATION AND SAFE

Por Le Moan, Natacha, Getz, Jen, Ng, Sarah, Davis, Tina, Bedard, Catherine, Davis, Andrew, Leung, Philberta, Serwer, Laura, Tanaka, Kevin, Keating, Tim, Yan, Feng, Winger, Jonathan, Cary, Stephen, Krtolica, Ana
Publicado em 2014

Modification by covalent reaction or oxidation of cysteine residues in the Tandem-SH2 Domains of ZAP-70 and Syk Can Block Phosphopeptide Binding

Por Visperas, Patrick R., Winger, Jonathan A., Horton, Timothy M., Shah, Neel H., Aum, Diane J., Tao, Alyssa, Barros, Tiago, Yan, Qingrong, Wilson, Christopher G., Arkin, Michelle R., Weiss, Arthur, Kuriyan, John
Publicado no Biochem J (2015)

ATPS-49 RESULTS OF A PHASE 0 CLINICAL TRIAL IN CANINE BRAIN CANCER EVALUATING SAFETY AND ACTIVITY OF OMX-4.80P, A PROTEIN OXYGEN CARRIER IND CANDIDATE FOR TREATMENT OF GLIOBLASTOMA

Por Leung, Philberta, Le Moan, Natacha, Getz, Jen, Ng, Sarah, Bedard, Catherine, Davis, Tina, Liang, Carol, Davis, Andrew, Serwer, Laura, Tanaka, Kevin, Keating, Tim, Yan, Feng, Winger, Jonathan, Sturges, Beverly, Guerrero, Teri, Dickinson, Peter, Kent, Michael, Cary, Stephen, Krtolica, Ana
Publicado no Neuro Oncol (2015)

NIMG-45 REAL-TIME PET IMAGING DEMONSTRATES TUMOR ACCUMULATION AND OXYGENATION BY OMX-4.80P, AN OXYGEN CARRIER ENGINEERED FOR THE TREATMENT OF GLIOBLASTOMA

Por Serwer, Laura, Le Moan, Natacha, Regan, Melanie, Blecha, Joseph, Davis, Andrew, Tanaka, Kevin, Keating, Tim, Romero, Jamie, Leung, Philberta, Davis, Tina, Bedard, Catherine, Ng, Sarah, Yan, Feng, Santos, Raquel, Ozawa, Tomoko, Butowski, Nicholas, Cary, Stephen, Nicolaides, Theodore, Seo, Youngho, Winger, Jonathan, VanBrocklin, Henry, Krtolica, Ana
Publicado no Neuro Oncol (2015)

Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic

Por Boehme, Jason, Le Moan, Natacha, Kameny, Rebecca J., Loucks, Alexandra, Johengen, Michael J., Lesneski, Amy L., Gong, Wenhui, Goudy, Brian D., Davis, Tina, Tanaka, Kevin, Davis, Andrew, He, Youping, Long-Boyle, Janel, Ivaturi, Vijay, Gobburu, Jogarao V. S., Winger, Jonathan A., Cary, Stephen P., Datar, Sanjeev A., Fineman, Jeffrey R., Krtolica, Ana, Maltepe, Emin
Publicado no PLoS Biol (2018)

Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic

Por Boehme, Jason, Le Moan, Natacha, Kameny, Rebecca J., Loucks, Alexandra, Johengen, Michael J., Lesneski, Amy L., Gong, Wenhui, Goudy, Brian D., Davis, Tina, Tanaka, Kevin, Davis, Andrew, He, Youping, Long-Boyle, Janel, Ivaturi, Vijay, Gobburu, Jogarao V. S., Winger, Jonathan A., Cary, Stephen P., Datar, Sanjeev A., Fineman, Jeffrey R., Krtolica, Ana, Maltepe, Emin
Publicado no PLoS Biol (2019)