Life in the balance: how BH3-only proteins induce apoptosis

di Willis, Simon N, Adams, Jerry M
Pubblicazione 2005

Immune surveillance of intracranial germ cell tumors

di Willis, Simon N., Mallozzi, Scott S., O’Connor, Kevin C.
Pubblicazione 2008

Investigating the Antigen Specificity of Multiple Sclerosis Central Nervous System-Derived Immunoglobulins

di Willis, Simon N., Stathopoulos, Panos, Chastre, Anne, Compton, Shannon D., Hafler, David A., O’Connor, Kevin C.
Pubblicato in Front Immunol (2015)

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x(L), but not Bcl-2, until displaced by BH3-only proteins

di Willis, Simon N., Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I., Adams, Jerry M., Huang, David C.S.
Pubblicazione 2005

Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1

di Kvansakul, Marc, Wei, Andrew H., Fletcher, Jamie I., Willis, Simon N., Chen, Lin, Roberts, Andrew W., Huang, David C. S., Colman, Peter M.
Pubblicazione 2010

Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis

di Lovato, Laura, Willis, Simon N., Rodig, Scott J., Caron, Tyler, Almendinger, Stefany E., Howell, Owain W., Reynolds, Richard, O’Connor, Kevin C., Hafler, David A.
Pubblicazione 2011

Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB

di Willis, Simon N., Tellier, Julie, Liao, Yang, Trezise, Stephanie, Light, Amanda, O’Donnell, Kristy, Garrett-Sinha, Lee Ann, Shi, Wei, Tarlinton, David M., Nutt, Stephen L.
Pubblicato in Nat Commun (2017)

Protein array–based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis

di Querol, Luis, Clark, Pamela L., Bailey, Mary A., Cotsapas, Chris, Cross, Anne H., Hafler, David A., Kleinstein, Steven H., Lee, Jae-Yun, Yaari, Gur, Willis, Simon N., O'Connor, Kevin C.
Pubblicazione 2013

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

di Lee, Erinna F., Czabotar, Peter E., van Delft, Mark F., Michalak, Ewa M., Boyle, Michelle J., Willis, Simon N., Puthalakath, Hamsa, Bouillet, Philippe, Colman, Peter M., Huang, David C.S., Fairlie, W. Douglas
Pubblicazione 2008

Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain

di Willis, Simon N., Stadelmann, Christine, Rodig, Scott J., Caron, Tyler, Gattenloehner, Stefan, Mallozzi, Scott S., Roughan, Jill E., Almendinger, Stefany E., Blewett, Megan M., Brück, Wolfgang, Hafler, David A., O’Connor, Kevin C.
Pubblicazione 2009

Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin

di Obermeier, Birgit, Lovato, Laura, Mentele, Reinhard, Brück, Wolfgang, Forne, Ignasi, Imhof, Axel, Lottspeich, Friedrich, Turk, Katherine W., Willis, Simon N., Wekerle, Hartmut, Hohlfeld, Reinhard, Hafler, David A., O'Connor, Kevin C., Dornmair, Klaus
Pubblicazione 2011

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

di van Delft, Mark F., Wei, Andrew H., Mason, Kylie D., Vandenberg, Cassandra J., Chen, Lin, Czabotar, Peter E., Willis, Simon N., Scott, Clare L., Day, Catherine L., Cory, Suzanne, Adams, Jerry M., Roberts, Andrew W., Huang, David C.S.
Pubblicazione 2006

Autoantibodies Produced at the Site of Tissue Damage Provide Evidence of Humoral Autoimmunity in Inclusion Body Myositis

di Ray, Arundhati, Amato, Anthony A., Bradshaw, Elizabeth M., Felice, Kevin J., DiCapua, Daniel B., Goldstein, Jonathan M., Lundberg, Ingrid E., Nowak, Richard J., Ploegh, Hidde L., Spooner, Eric, Wu, Qian, Willis, Simon N., O’Connor, Kevin C.
Pubblicazione 2012

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

di Carotta, Sebastian, Willis, Simon N., Hasbold, Jhagvaral, Inouye, Michael, Pang, Swee Heng Milon, Emslie, Dianne, Light, Amanda, Chopin, Michael, Shi, Wei, Wang, Hongsheng, Morse, Herbert C., Tarlinton, David M., Corcoran, Lynn M., Hodgkin, Philip D., Nutt, Stephen L.
Pubblicazione 2014

Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1

di Huntington, Nicholas D, Puthalakath, Hamsa, Gunn, Priscilla, Naik, Edwina, Michalak, Ewa M, Smyth, Mark J, Tabarias, Hyacinth, Degli-Esposti, Mariapia A, Dewson, Grant, Willis, Simon N, Motoyama, Noboru, Huang, David C S, Nutt, Stephen L, Tarlinton, David M, Strasser, Andreas
Pubblicazione 2007

Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins

di Trezise, Stephanie, Karnowski, Alexander, Fedele, Pasquale L., Mithraprabhu, Sridurga, Liao, Yang, D’Costa, Kathy, Kueh, Andrew J., Hardy, Matthew P., Owczarek, Catherine M., Herold, Marco J., Spencer, Andrew, Shi, Wei, Willis, Simon N., Nutt, Stephen L., Corcoran, Lynn M.
Pubblicato in Int J Mol Sci (2018)

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

di de Valle, Elisha, Grigoriadis, George, O’Reilly, Lorraine A., Willis, Simon N., Maxwell, Mhairi J., Corcoran, Lynn M., Tsantikos, Evelyn, Cornish, Jasper K.S., Fairfax, Kirsten A., Vasanthakumar, Ajithkumar, Febbraio, Mark A., Hibbs, Margaret L., Pellegrini, Marc, Banerjee, Ashish, Hodgkin, Philip D., Kallies, Axel, Mackay, Fabienne, Strasser, Andreas, Gerondakis, Steve, Gugasyan, Raffi
Pubblicato in J Exp Med (2016)

A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets

di Almeida, Francisca F., Tognarelli, Sara, Marçais, Antoine, Kueh, Andrew J., Friede, Miriam E., Liao, Yang, Willis, Simon N., Luong, Kylie, Faure, Fabrice, Mercier, Francois E., Galluso, Justine, Firth, Matthew, Narni-Mancinelli, Emilie, Rais, Bushra, Scadden, David T., Spallotta, Francesco, Weil, Sandra, Giannattasio, Ariane, Kalensee, Franziska, Zöller, Tobias, Huntington, Nicholas D., Schleicher, Ulrike, Chiocchetti, Andreas G., Ugolini, Sophie, Herold, Marco J., Shi, Wei, Koch, Joachim, Steinle, Alexander, Vivier, Eric, Walzer, Thierry, Belz, Gabrielle T., Ullrich, Evelyn
Pubblicato in Oncoimmunology (2018)