Point mutation increases a form of the NK(1) receptor with high affinity for neurokinin A and B and septide

Por Ciucci, Alessandra, Palma, Carla, Manzini, Stefano, Werge, Thomas M
Publicado em 1998

Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions

Por Giovanoli, Sandra, Werge, Thomas M., Mortensen, Preben B., Didriksen, Michael, Meyer, Urs
Publicado no Neuropsychopharmacology (2018)

AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

Por Nagy, Stanislav, Maurer, Gianna W., Hentze, Julie L., Rose, Morten, Werge, Thomas M., Rewitz, Kim
Publicado no PLoS Genet (2018)

Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register

Por Hilker, Rikke, Helenius, Dorte, Fagerlund, Birgitte, Skytthe, Axel, Christensen, Kaare, Werge, Thomas M., Nordentoft, Merete, Glenthøj, Birte
Publicado no EBioMedicine (2017)

Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control

Por Maurer, Gianna W., Malita, Alina, Nagy, Stanislav, Koyama, Takashi, Werge, Thomas M., Halberg, Kenneth A., Texada, Michael J., Rewitz, Kim
Publicado no PLoS Genet (2020)

Investigation of SNP rs2060546 Immediately Upstream to NTN4 in a Danish Gilles de la Tourette Syndrome Cohort

Por Padmanabhuni, Shanmukha S., Houssari, Rayan, Esserlind, Ann-Louise, Olesen, Jes, Werge, Thomas M., Hansen, Thomas F., Bertelsen, Birgitte, Tsetsos, Fotis, Paschou, Peristera, Tümer, Zeynep
Publicado no Front Neurosci (2016)

Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap

Por Gandal, Michael J., Haney, Jillian R., Parikshak, Neelroop N., Leppa, Virpi, Ramaswami, Gokul, Hartl, Chris, Schork, Andrew J., Appadurai, Vivek, Buil, Alfonso, Werge, Thomas M., Liu, Chunyu, White, Kevin P., Geschwind, Daniel H.
Publicado no Focus (Am Psychiatr Publ) (2019)

A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission

Por Nielsen, Jacob, Fejgin, Kim, Sotty, Florence, Nielsen, Vibeke, Mørk, Arne, Christoffersen, Claus T., Yavich, Leonid, Lauridsen, Jes B., Clausen, Dorte, Larsen, Peter H., Egebjerg, Jan, Werge, Thomas M., Kallunki, Pekka, Christensen, Kenneth V., Didriksen, Michael
Publicado no Transl Psychiatry (2017)

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

Por Gandal, Michael J., Haney, Jillian R., Parikshak, Neelroop N., Leppa, Virpi, Ramaswami, Gokul, Hartl, Chris, Schork, Andrew J., Appadurai, Vivek, Buil, Alfonso, Werge, Thomas M., Liu, Chunyu, White, Kevin P., Horvath, Steve, Geschwind, Daniel H.
Publicado no Science (2018)

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease

Por Hagen, Christian M., Gonçalves, Vanessa F., Hedley, Paula L., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Hansen, Christine S., Kanters, Jørgen K., Nielsen, Jimmi, Mors, Ole, Demur, Alfonso B., Als, Thomas D., Nordentoft, Merete, Børglum, Anders, Mortensen, Preben B., Kennedy, James, Werge, Thomas M., Hougaard, David M., Christiansen, Michael
Publicado no PLoS One (2018)

Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice

Por Didriksen, Michael, Fejgin, Kim, Nilsson, Simon R.O., Birknow, Michelle R., Grayton, Hannah M., Larsen, Peter H., Lauridsen, Jes B., Nielsen, Vibeke, Celada, Pau, Santana, Noemi, Kallunki, Pekka, Christensen, Kenneth V., Werge, Thomas M., Stensbøl, Tine B., Egebjerg, Jan, Gastambide, Francois, Artigas, Francesc, Bastlund, Jesper F., Nielsen, Jacob
Publicado no J Psychiatry Neurosci (2017)

Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes

Por Bybjerg-Grauholm, Jonas, Hagen, Christian M., Gonçalves, Vanessa F., Bækvad-Hansen, Marie, Hansen, Christine S., Hedley, Paula L., Kanters, Jørgen K., Nielsen, Jimmi, Theisen, Michael, Mors, Ole, Kennedy, James, Als, Thomas D., Demur, Alfonso B., Nordentoft, Merete, Børglum, Anders, Mortensen, Preben B., Werge, Thomas M., Hougaard, David M., Christiansen, Michael
Publicado no PLoS One (2018)

Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have a similar burden of rare protein-truncating variants

Por Satterstrom, F. Kyle, Walters, Raymond K., Singh, Tarjinder, Wigdor, Emilie M., Lescai, Francesco, Demontis, Ditte, Kosmicki, Jack A., Grove, Jakob, Stevens, Christine, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Palmer, Duncan S., Maller, Julian B., Nordentoft, Merete, Mors, Ole, Robinson, Elise B., Hougaard, David M., Werge, Thomas M., Mortensen, Preben Bo, Neale, Benjamin M., Børglum, Anders D., Daly, Mark J.
Publicado no Nat Neurosci (2019)

Quetiapine versus aripiprazole in children and adolescents with psychosis - protocol for the randomised, blinded clinical Tolerability and Efficacy of Antipsychotics (TEA) trial

Por Pagsberg, Anne Katrine, Jeppesen, Pia, Klauber, Dea Gowers, Jensen, Karsten Gjessing, Rudå, Ditte, Stentebjerg-Olesen, Marie, Jantzen, Peter, Rasmussen, Simone, Saldeen, Eva Ann-Sofie, Lauritsen, Maj-Britt Glenn, Bilenberg, Niels, Stenstrøm, Anne Dorte, Pedersen, Jesper, Nyvang, Louise, Madsen, Sarah, Lauritsen, Marlene B, Vernal, Ditte Lammers, Thomsen, Per Hove, Paludan, Jakob, Werge, Thomas M, Winge, Kristian, Juul, Klaus, Gluud, Christian, Skoog, Maria, Wetterslev, Jørn, Jepsen, Jens Richardt M, Correll, Christoph U, Fink-Jensen, Anders, Fagerlund, Birgitte
Publicado no BMC Psychiatry (2014)

Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders

Por Isles, Anthony R., Ingason, Andrés, Lowther, Chelsea, Walters, James, Gawlick, Micha, Stöber, Gerald, Rees, Elliott, Martin, Joanna, Little, Rosie B., Potter, Harry, Georgieva, Lyudmila, Pizzo, Lucilla, Ozaki, Norio, Aleksic, Branko, Kushima, Itaru, Ikeda, Masashi, Iwata, Nakao, Levinson, Douglas F., Gejman, Pablo V., Shi, Jianxin, Sanders, Alan R., Duan, Jubao, Willis, Joseph, Sisodiya, Sanjay, Costain, Gregory, Werge, Thomas M., Degenhardt, Franziska, Giegling, Ina, Rujescu, Dan, Hreidarsson, Stefan J., Saemundsen, Evald, Ahn, Joo Wook, Ogilvie, Caroline, Girirajan, Santhosh D., Stefansson, Hreinn, Stefansson, Kari, O’Donovan, Michael C., Owen, Michael J., Bassett, Anne, Kirov, George
Publicado no PLoS Genet (2016)

Population genetic differentiation of height and body mass index across Europe

Por Robinson, Matthew R., Hemani, Gibran, Medina-Gomez, Carolina, Mezzavilla, Massimo, Esko, Tonu, Shakhbazov, Konstantin, Powell, Joseph E., Vinkhuyzen, Anna, Berndt, Sonja I., Gustafsson, Stefan, Justice, Anne E., Kahali, Bratati, Locke, Adam E., Pers, Tune H., Vedantam, Sailaja, Wood, Andrew R., van Rheenen, Wouter, Andreassen, Ole A., Gasparini, Paolo, Metspalu, Andres, van den Berg, Leonard H., Veldink, Jan H., Rivadeneira, Fernando, Werge, Thomas M., Abecasis, Goncalo R., Boomsma, Dorret I., Chasman, Daniel I., de Geus, Eco J.C., Frayling, Timothy M., Hirschhorn, Joel N., Hottenga, Jouke Jan, Ingelsson, Erik, Loos, Ruth J.F., Magnusson, Patrik K. E., Martin, Nicholas G., Montgomery, Grant W., North, Kari E., Pedersen, Nancy L., Spector, Timothy D., Speliotes, Elizabeth K., Goddard, Michael E., Yang, Jian, Visscher, Peter M.
Publicado no Nat Genet (2015)

The Anorexia Nervosa Genetics Initiative (ANGI): Overview and Methods

Por Thornton, Laura M, Munn-Chernoff, Melissa A, Baker, Jessica H, Juréus, Anders, Parker, Richard, Henders, Anjali K, Larsen, Janne T, Petersen, Liselotte, Watson, Hunna J, Yilmaz, Zeynep, Kirk, Katherine M, Gordon, Scott, Leppä, Virpi M, Martin, Felicity C, Whiteman, David C, Olsen, Catherine M, Werge, Thomas M, Pedersen, Nancy L, Kaye, Walter, Bergen, Andrew W, Halmi, Katherine A, Strober, Michael, Kaplan, Allan S, Woodside, D. Blake, Mitchell, James, Johnson, Craig L, Brandt, Harry, Crawford, Steven, Horwood, L. John, Boden, Joseph M, Pearson, John F, Duncan, Laramie E, Grove, Jakob, Mattheisen, Manuel, Jordan, Jennifer, Kennedy, Martin A, Birgegård, Andreas, Lichtenstein, Paul, Norring, Claes, Wade, Tracey D, Montgomery, Grant W, Martin, Nicholas G, Landén, Mikael, Bo Mortensen, Preben, Sullivan, Patrick F, Bulik, Cynthia M
Publicado no Contemp Clin Trials (2018)

Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes

Por Delio, Maria, Guo, Tingwei, McDonald-McGinn, Donna M., Zackai, Elaine, Herman, Sean, Kaminetzky, Mark, Higgins, Anne Marie, Coleman, Karlene, Chow, Carolyn, Jarlbrzkowski, Maria, Bearden, Carrie E., Bailey, Alice, Vangkilde, Anders, Olsen, Line, Olesen, Charlotte, Skovby, Flemming, Werge, Thomas M., Templin, Ludivine, Busa, Tiffany, Philip, Nicole, Swillen, Ann, Vermeesch, Joris R., Devriendt, Koen, Schneider, Maude, Dahoun, Sophie, Eliez, Stephan, Schoch, Kelly, Hooper, Stephen R., Shashi, Vandana, Samanich, Joy, Marion, Robert, van Amelsvoort, Therese, Boot, Erik, Klaassen, Petra, Duijff, Sasja N., Vorstman, Jacob, Yuen, Tracy, Silversides, Candice, Chow, Eva, Bassett, Anne, Frisch, Amos, Weizman, Abraham, Gothelf, Doron, Niarchou, Maria, van den Bree, Marianne, Owen, Michael J., Suñer, Damian Heine, Andreo, Jordi Rosell, Armando, Marco, Vicari, Stefano, Digilio, Maria Cristina, Auton, Adam, Kates, Wendy R., Wang, Tao, Shprintzen, Robert J., Emanuel, Beverly S., Morrow, Bernice E.
Publicado em 2013

Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes

Por Delio, Maria, Guo, Tingwei, McDonald-McGinn, Donna M., Zackai, Elaine, Herman, Sean, Kaminetzky, Mark, Higgins, Anne Marie, Coleman, Karlene, Chow, Carolyn, Jalbrzikowski, Maria, Bearden, Carrie E., Bailey, Alice, Vangkilde, Anders, Olsen, Line, Olesen, Charlotte, Skovby, Flemming, Werge, Thomas M., Templin, Ludivine, Busa, Tiffany, Philip, Nicole, Swillen, Ann, Vermeesch, Joris R., Devriendt, Koen, Schneider, Maude, Dahoun, Sophie, Eliez, Stephan, Schoch, Kelly, Hooper, Stephen R., Shashi, Vandana, Samanich, Joy, Marion, Robert, van Amelsvoort, Therese, Boot, Erik, Klaassen, Petra, Duijff, Sasja N., Vorstman, Jacob, Yuen, Tracy, Silversides, Candice, Chow, Eva, Bassett, Anne, Frisch, Amos, Weizman, Abraham, Gothelf, Doron, Niarchou, Maria, van den Bree, Marianne, Owen, Michael J., Suñer, Damian Heine, Andreo, Jordi Rosell, Armando, Marco, Vicari, Stefano, Digilio, Maria Cristina, Auton, Adam, Kates, Wendy R., Wang, Tao, Shprintzen, Robert J., Emanuel, Beverly S., Morrow, Bernice E.
Publicado em 2013

An epigenetic clock for gestational age at birth based on blood methylation data

Por Knight, Anna K., Craig, Jeffrey M., Theda, Christiane, Bækvad-Hansen, Marie, Bybjerg-Grauholm, Jonas, Hansen, Christine S., Hollegaard, Mads V., Hougaard, David M., Mortensen, Preben B., Weinsheimer, Shantel M., Werge, Thomas M., Brennan, Patricia A., Cubells, Joseph F., Newport, D. Jeffrey, Stowe, Zachary N., Cheong, Jeanie L. Y., Dalach, Philippa, Doyle, Lex W., Loke, Yuk J., Baccarelli, Andrea A., Just, Allan C., Wright, Robert O., Téllez-Rojo, Mara M., Svensson, Katherine, Trevisi, Letizia, Kennedy, Elizabeth M., Binder, Elisabeth B., Iurato, Stella, Czamara, Darina, Räikkönen, Katri, Lahti, Jari M. T., Pesonen, Anu-Katriina, Kajantie, Eero, Villa, Pia M., Laivuori, Hannele, Hämäläinen, Esa, Park, Hea Jin, Bailey, Lynn B., Parets, Sasha E., Kilaru, Varun, Menon, Ramkumar, Horvath, Steve, Bush, Nicole R., LeWinn, Kaja Z., Tylavsky, Frances A., Conneely, Karen N., Smith, Alicia K.
Publicado no Genome Biol (2016)