ロード中...

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

The predisposition to neuropsychiatric disease involves a complex, polygenic, and pleiotropic genetic architecture. However, little is known about how genetic variants impart brain dysfunction or pathology. We use transcriptomic profiling as a quantitative readout of molecular brain-based phenotypes...

詳細記述

保存先:
書誌詳細
出版年:Science
主要な著者: Gandal, Michael J., Haney, Jillian R., Parikshak, Neelroop N., Leppa, Virpi, Ramaswami, Gokul, Hartl, Chris, Schork, Andrew J., Appadurai, Vivek, Buil, Alfonso, Werge, Thomas M., Liu, Chunyu, White, Kevin P., Horvath, Steve, Geschwind, Daniel H.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898828/
https://ncbi.nlm.nih.gov/pubmed/29439242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad6469
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!