Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism

Autism spectrum disorder (ASD) involves substantial genetic contributions. These contributions are profoundly heterogeneous but may converge on common pathways that are not yet well understood(1–3). Here, through post-mortem genome-wide transcriptome analysis of the largest cohort of samples analyse...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Parikshak, Neelroop N., Swarup, Vivek, Belgard, T. Grant, Irimia, Manuel, Ramaswami, Gokul, Gandal, Michael J., Hartl, Christopher, Leppa, Virpi, de la Torre Ubieta, Luis, Huang, Jerry, Lowe, Jennifer K., Blencowe, Benjamin J., Horvath, Steve, Geschwind, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102905/
https://ncbi.nlm.nih.gov/pubmed/27919067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20612
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