Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism

Autism spectrum disorder (ASD) involves substantial genetic contributions. These contributions are profoundly heterogeneous but may converge on common pathways that are not yet well understood(1–3). Here, through post-mortem genome-wide transcriptome analysis of the largest cohort of samples analyse...

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Veröffentlicht in:Nature
Hauptverfasser: Parikshak, Neelroop N., Swarup, Vivek, Belgard, T. Grant, Irimia, Manuel, Ramaswami, Gokul, Gandal, Michael J., Hartl, Christopher, Leppa, Virpi, de la Torre Ubieta, Luis, Huang, Jerry, Lowe, Jennifer K., Blencowe, Benjamin J., Horvath, Steve, Geschwind, Daniel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102905/
https://ncbi.nlm.nih.gov/pubmed/27919067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20612
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