Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease

Mitochondria play a significant role in human diseases. However, disease associations with mitochondrial DNA (mtDNA) SNPs have proven difficult to replicate. An analysis of eight schizophrenia-associated mtDNA SNPs, in 23,743 Danes without a psychiatric diagnosis and 2,538 schizophrenia patients, re...

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Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Hagen, Christian M., Gonçalves, Vanessa F., Hedley, Paula L., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Hansen, Christine S., Kanters, Jørgen K., Nielsen, Jimmi, Mors, Ole, Demur, Alfonso B., Als, Thomas D., Nordentoft, Merete, Børglum, Anders, Mortensen, Preben B., Kennedy, James, Werge, Thomas M., Hougaard, David M., Christiansen, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287820/
https://ncbi.nlm.nih.gov/pubmed/30532134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208828
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