An epigenetic clock for gestational age at birth based on blood methylation data

BACKGROUND: Gestational age is often used as a proxy for developmental maturity by clinicians and researchers alike. DNA methylation has previously been shown to be associated with age and has been used to accurately estimate chronological age in children and adults. In the current study, we examine...

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Udgivet i:Genome Biol
Main Authors: Knight, Anna K., Craig, Jeffrey M., Theda, Christiane, Bækvad-Hansen, Marie, Bybjerg-Grauholm, Jonas, Hansen, Christine S., Hollegaard, Mads V., Hougaard, David M., Mortensen, Preben B., Weinsheimer, Shantel M., Werge, Thomas M., Brennan, Patricia A., Cubells, Joseph F., Newport, D. Jeffrey, Stowe, Zachary N., Cheong, Jeanie L. Y., Dalach, Philippa, Doyle, Lex W., Loke, Yuk J., Baccarelli, Andrea A., Just, Allan C., Wright, Robert O., Téllez-Rojo, Mara M., Svensson, Katherine, Trevisi, Letizia, Kennedy, Elizabeth M., Binder, Elisabeth B., Iurato, Stella, Czamara, Darina, Räikkönen, Katri, Lahti, Jari M. T., Pesonen, Anu-Katriina, Kajantie, Eero, Villa, Pia M., Laivuori, Hannele, Hämäläinen, Esa, Park, Hea Jin, Bailey, Lynn B., Parets, Sasha E., Kilaru, Varun, Menon, Ramkumar, Horvath, Steve, Bush, Nicole R., LeWinn, Kaja Z., Tylavsky, Frances A., Conneely, Karen N., Smith, Alicia K.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054584/
https://ncbi.nlm.nih.gov/pubmed/27717399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1068-z
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