Role of Reactive Oxygen Species in Neonatal Pulmonary Vascular Disease

por Wedgwood, Stephen, Steinhorn, Robin H.
Publicado 2014

Protein kinase Cδ regulates endothelial nitric oxide synthase expression via Akt activation and nitric oxide generation

por Sud, Neetu, Wedgwood, Stephen, Black, Stephen M.
Publicado 2008

Optimal oxygenation and role of free radicals in PPHN

por Wedgwood, Stephen, Steinhorn, Robin H., Lakshminrusimha, Satyan
Publicado en Free Radic Biol Med (2019)

Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of AP-1 activity

por Kumar, Sanjiv, Sun, Xutong, Wedgwood, Stephen, Black, Stephen M.
Publicado 2008

Modulation of PKCδ signaling alters the shear stress-mediated increases in endothelial nitric oxide synthase transcription: role of STAT3

por Sud, Neetu, Kumar, Sanjiv, Wedgwood, Stephen, Black, Stephen M.
Publicado 2009

Regulation of fibroblast growth factor-2 expression in pulmonary arterial smooth muscle cells involves increased reactive oxygen species generation

por Black, Stephen M., DeVol, Jennifer M., Wedgwood, Stephen
Publicado 2008

Hypoxia inducible factor signaling and experimental persistent pulmonary hypertension of the newborn

por Wedgwood, Stephen, Lakshminrusimha, Satyan, Schumacker, Paul T., Steinhorn, Robin H.
Publicado en Front Pharmacol (2015)

Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells

por Wedgwood, Stephen, Lakshminrusimha, Satyan, Schumacker, Paul T., Steinhorn, Robin H.
Publicado en Am J Physiol Lung Cell Mol Physiol (2015)

Increased p22(phox)/Nox4 Expression Is Involved in Remodeling Through Hydrogen Peroxide Signaling in Experimental Persistent Pulmonary Hypertension of the Newborn

por Wedgwood, Stephen, Lakshminrusimha, Satyan, Czech, Lyubov, Schumacker, Paul T., Steinhorn, Robin H.
Publicado 2013

Hydrocortisone normalizes phosphodiesterase-5 activity in pulmonary artery smooth muscle cells from lambs with persistent pulmonary hypertension of the newborn

por Perez, Marta, Wedgwood, Stephen, Lakshminrusimha, Satyan, Farrow, Kathryn N., Steinhorn, Robin H.
Publicado 2014

Hydrogen Peroxide Regulates Extracellular Superoxide Dismutase Activity and Expression in Neonatal Pulmonary Hypertension

por Wedgwood, Stephen, Lakshminrusimha, Satyan, Fukai, Tohru, Russell, James A., Schumacker, Paul T., Steinhorn, Robin H.
Publicado 2011

Inhaled Nitric Oxide at Birth Reduces Pulmonary Vascular Resistance and Improves Oxygenation in Preterm Lambs

por Lakshminrusimha, Satyan, Gugino, Sylvia F., Sekar, Krishnamurthy, Wedgwood, Stephen, Koenigsknecht, Carmon, Nair, Jayasree, Mathew, Bobby
Publicado en Children (Basel) (2021)

Increased hydrogen peroxide downregulates soluble guanylate cyclase in the lungs of lambs with persistent pulmonary hypertension of the newborn

por Wedgwood, Stephen, Steinhorn, Robin H., Bunderson, Melisa, Wilham, Jason, Lakshminrusimha, Satyan, Brennan, Lisa A., Black, Stephen M.
Publicado 2005

Developmental Differences in Hyperoxia-Induced Oxidative Stress and Cellular Responses in the Murine Lung

por Berkelhamer, Sara K., Kim, Gina A., Radder, Josiah E., Wedgwood, Stephen, Czech, Lyubov, Steinhorn, Robin H., Schumacker, Paul T.
Publicado 2013

Superoxide Dismutase Improves Oxygenation and Reduces Oxidation in Neonatal Pulmonary Hypertension

por Lakshminrusimha, Satyan, Russell, James A., Wedgwood, Stephen, Gugino, Sylvia F., Kazzaz, Jeffrey A., Davis, Jonathan M., Steinhorn, Robin H.
Publicado 2006

MITOCHONDRIAL OXIDANT STRESS INCREASES PDE5 ACTIVITY IN PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN

por Farrow, Kathryn N., Wedgwood, Stephen, Lee, Keng Jin, Czech, Lyubov, Gugino, Sylvia F., Lakshminrusimha, Satyan, Schumacker, Paul T., Steinhorn, Robin H.
Publicado 2010

Apocynin improves oxygenation and increases eNOS in persistent pulmonary hypertension of the newborn

por Wedgwood, Stephen, Lakshminrusimha, Satyan, Farrow, Kathryn N., Czech, Lyubov, Gugino, Sylvia F., Soares, Fernando, Russell, James A., Steinhorn, Robin H.
Publicado 2012

Hydrocortisone normalizes oxygenation and cGMP regulation in lambs with persistent pulmonary hypertension of the newborn

por Perez, Marta, Lakshminrusimha, Satyan, Wedgwood, Stephen, Czech, Lyubov, Gugino, Sylvia F., Russell, James A., Farrow, Kathryn N., Steinhorn, Robin H.
Publicado 2012

Cyclic Stretch Induces Inducible Nitric Oxide Synthase and Soluble Guanylate Cyclase in Pulmonary Artery Smooth Muscle Cells

por Shah, Monica R., Wedgwood, Stephen, Czech, Lyubov, Kim, Gina A., Lakshminrusimha, Satyan, Schumacker, Paul T., Steinhorn, Robin H., Farrow, Kathryn N.
Publicado 2013

Optimal Oxygen Targets in Term Lambs with Meconium Aspiration Syndrome and Pulmonary Hypertension

por Rawat, Munmun, Chandrasekharan, Praveen, Gugino, Sylvia F., Koenigsknecht, Carmon, Nielsen, Lori, Wedgwood, Stephen, Mathew, Bobby, Nair, Jayasree, Steinhorn, Robin, Lakshminrusimha, Satyan
Publicado en Am J Respir Cell Mol Biol (2020)