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Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of AP-1 activity

Previously, we have reported that endothelial nitric oxide synthase (eNOS) promoter activity is decreased in pulmonary arterial endothelial cells (PAECs) in response to hydrogen peroxide (H(2)O(2)). Thus the objective of this study was to identify the cis-element(s) and transcription factor(s) respo...

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Autors principals: Kumar, Sanjiv, Sun, Xutong, Wedgwood, Stephen, Black, Stephen M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519847/
https://ncbi.nlm.nih.gov/pubmed/18556800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90205.2008
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