Hydrogen Peroxide Decreases Endothelial Nitric Oxide Synthase Promoter Activity through the Inhibition of Sp1 Activity

We have previously shown that endothelial nitric oxide synthase (eNOS) promoter activity is decreased in endothelial cells in response to the addition of hydrogen peroxide (H(2)O(2)), and this involves, at least in part, the inhibition of AP-1 activity. Thus, the objective of this study was to deter...

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Hlavní autoři: Kumar, Sanjiv, Sun, Xutong, Wiseman, Dean A., Tian, Jing, Umapathy, Nagavedi S., Verin, Alexander D., Black, Stephen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2009
Témata:
Original Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668153/
https://ncbi.nlm.nih.gov/pubmed/19105596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2008.0775
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