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Caveolin 1 Is Required for the Activation of Endothelial Nitric Oxide Synthase in Response to 17β-Estradiol

Evidence suggests that estrogen mediates rapid endothelial nitric oxide synthase (eNOS) activation via estrogen receptor-a (ERα) within the plasma membrane of endothelial cells (EC). ERα is known to colocalize with caveolin 1, the major structural protein of caveolae, and caveolin 1 stimulates the t...

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Bibliographic Details
Main Authors: Sud, Neetu, Wiseman, Dean A., Black, Stephen M.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940462/
https://ncbi.nlm.nih.gov/pubmed/20610538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0043
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