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Caveolin 1 Is Required for the Activation of Endothelial Nitric Oxide Synthase in Response to 17β-Estradiol
Evidence suggests that estrogen mediates rapid endothelial nitric oxide synthase (eNOS) activation via estrogen receptor-a (ERα) within the plasma membrane of endothelial cells (EC). ERα is known to colocalize with caveolin 1, the major structural protein of caveolae, and caveolin 1 stimulates the t...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
The Endocrine Society
2010
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940462/ https://ncbi.nlm.nih.gov/pubmed/20610538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0043 |
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