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Protein kinase Cδ regulates endothelial nitric oxide synthase expression via Akt activation and nitric oxide generation

In this study, we explore the roles of the delta isoform of PKC (PKCδ) in the regulation of endothelial nitric oxide synthase (eNOS) activity in pulmonary arterial endothelial cells isolated from fetal lambs (FPAECs). Pharmacological inhibition of PKCδ with either rottlerin or with the peptide, δV1-...

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Detalhes bibliográficos
Main Authors: Sud, Neetu, Wedgwood, Stephen, Black, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970932/
https://ncbi.nlm.nih.gov/pubmed/18192589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00353.2007
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