Apocynin improves oxygenation and increases eNOS in persistent pulmonary hypertension of the newborn

NADPH oxidase is a major source of superoxide anions in the pulmonary arteries (PA). We previously reported that intratracheal SOD improves oxygenation and restores endothelial nitric oxide (NO) synthase (eNOS) function in lambs with persistent pulmonary hypertension of the newborn (PPHN). In this s...

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Detalhes bibliográficos
Main Authors: Wedgwood, Stephen, Lakshminrusimha, Satyan, Farrow, Kathryn N., Czech, Lyubov, Gugino, Sylvia F., Soares, Fernando, Russell, James A., Steinhorn, Robin H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311530/
https://ncbi.nlm.nih.gov/pubmed/22198908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00064.2011
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