Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension

Endothelial nitric oxide (NO) synthase (eNOS) expression and activity are decreased in fetal lambs with persistent pulmonary hypertension (PPHN). We sought to determine the impact of mechanical ventilation with O(2) with or without inhaled NO (iNO) or recombinant human SOD (rhSOD) on eNOS in the duc...

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Detalhes bibliográficos
Main Authors: Farrow, Kathryn N., Lakshminrusimha, Satyan, Reda, William J., Wedgwood, Stephen, Czech, Lyubov, Gugino, Sylvia F., Davis, Jonathan M., Russell, James A., Steinhorn, Robin H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Editorial Focus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604791/
https://ncbi.nlm.nih.gov/pubmed/18790993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90238.2008
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