Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension

Endothelial nitric oxide (NO) synthase (eNOS) expression and activity are decreased in fetal lambs with persistent pulmonary hypertension (PPHN). We sought to determine the impact of mechanical ventilation with O(2) with or without inhaled NO (iNO) or recombinant human SOD (rhSOD) on eNOS in the duc...

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Hauptverfasser: Farrow, Kathryn N., Lakshminrusimha, Satyan, Reda, William J., Wedgwood, Stephen, Czech, Lyubov, Gugino, Sylvia F., Davis, Jonathan M., Russell, James A., Steinhorn, Robin H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604791/
https://ncbi.nlm.nih.gov/pubmed/18790993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90238.2008
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