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Hypoxia inducible factor signaling and experimental persistent pulmonary hypertension of the newborn

Background: Mitochondrial reactive oxygen species (ROS) levels and nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) activity are increased in a lamb model of persistent pulmonary hypertension of the newborn (PPHN). These events can trigger hypoxia inducible factor (HIF) signalin...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wedgwood, Stephen, Lakshminrusimha, Satyan, Schumacker, Paul T., Steinhorn, Robin H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356070/
https://ncbi.nlm.nih.gov/pubmed/25814954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00047
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