Toll and IMD Pathways Synergistically Activate an Innate Immune Response in Drosophila melanogaster

Por Tanji, Takahiro, Hu, Xiaodi, Weber, Alexander N. R., Ip, Y. Tony
Publicado em 2007

Gadd45a Is an RNA Binding Protein and Is Localized in Nuclear Speckles

Por Sytnikova, Yuliya A., Kubarenko, Andriy V., Schäfer, Andrea, Weber, Alexander N. R., Niehrs, Christof
Publicado em 2011

Comprehensive modeling and functional analysis of Toll-like receptor ligand-recognition domains

Por Kubarenko, Andriy V, Ranjan, Satish, Colak, Elif, George, Julie, Frank, Martin, Weber, Alexander N R
Publicado em 2010

Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA

Por Wang, Lihui, Weber, Alexander N R, Atilano, Magda L, Filipe, Sergio R, Gay, Nicholas J, Ligoxygakis, Petros
Publicado em 2006

Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury

Por Kruger, Philipp, Saffarzadeh, Mona, Weber, Alexander N. R., Rieber, Nikolaus, Radsak, Markus, von Bernuth, Horst, Benarafa, Charaf, Roos, Dirk, Skokowa, Julia, Hartl, Dominik
Publicado no PLoS Pathog (2015)

Two Human MYD88 Variants, S34Y and R98C, Interfere with MyD88-IRAK4-Myddosome Assembly

Por George, Julie, Motshwene, Precious G., Wang, Hui, Kubarenko, Andriy V., Rautanen, Anna, Mills, Tara C., Hill, Adrian V. S., Gay, Nicholas J., Weber, Alexander N. R.
Publicado em 2011

Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation

Por Shatnyeva, Olga M., Kubarenko, Andriy V., Weber, Claudia E. M., Pappa, Alexander, Schwartz-Albiez, Reinhard, Weber, Alexander N. R., Krammer, Peter H., Lavrik, Inna N.
Publicado em 2011

The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold

Por Dossang, Anthony C. G., Motshwene, Precious G., Yang, Yang, Symmons, Martyn F., Bryant, Clare E., Borman, Satty, George, Julie, Weber, Alexander N. R., Gay, Nicholas J.
Publicado no Sci Rep (2016)

Pattern recognition receptor mediated downregulation of microRNA‐650 fine‐tunes MxA expression in dendritic cells infected with influenza A virus

Por Pichulik, Tica, Khatamzas, Elham, Liu, Xiao, Brain, Oliver, Delmiro Garcia, Magno, Leslie, Alasdair, Danis, Benedicte, Mayer, Alice, Baban, Dilair, Ragoussis, Jiannis, Weber, Alexander N. R., Simmons, Alison
Publicado no Eur J Immunol (2015)

A Naturally Occurring Variant in Human TLR9, P99L, Is Associated with Loss of CpG Oligonucleotide Responsiveness

Por Kubarenko, Andriy V., Ranjan, Satish, Rautanen, Anna, Mills, Tara C., Wong, Sunny, Vannberg, Fredrik, Neumaier, Michael, Bekeredjian-Ding, Isabelle, Hill, Adrian V. S., Ahmad-Nejad, Parviz, Weber, Alexander N. R.
Publicado em 2010

Activation of lymphoma-associated MyD88 mutations via allostery-induced TIR-domain oligomerization

Por Avbelj, Monika, Wolz, Olaf-Oliver, Fekonja, Ota, Benčina, Mojca, Repič, Matej, Mavri, Janez, Krüger, Jens, Schärfe, Charlotta, Delmiro Garcia, Magno, Panter, Gabriela, Kohlbacher, Oliver, Weber, Alexander N. R., Jerala, Roman
Publicado no Blood (2014)

Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling

Por Paquette, Nicholas, Conlon, Joseph, Sweet, Charles, Rus, Florentina, Wilson, Lindsay, Pereira, Andrea, Rosadini, Charles V., Goutagny, Nadege, Weber, Alexander N. R., Lane, William S., Shaffer, Scott A., Maniatis, Stephanie, Fitzgerald, Katherine A., Stuart, Lynda, Silverman, Neal
Publicado em 2012

Study of Human RIG-I Polymorphisms Identifies Two Variants with an Opposite Impact on the Antiviral Immune Response

Por Pothlichet, Julien, Burtey, Anne, Kubarenko, Andriy V., Caignard, Gregory, Solhonne, Brigitte, Tangy, Frédéric, Ben-Ali, Meriem, Quintana-Murci, Lluis, Heinzmann, Andrea, Chiche, Jean-Daniel, Vidalain, Pierre-Olivier, Weber, Alexander N. R., Chignard, Michel, Si-Tahar, Mustapha
Publicado em 2009

Heterozygous Carriage of a Dysfunctional Toll-like Receptor 9 Allele Affects CpG Oligonucleotide Responses in B Cells

Por Knežević, Jelena, Pavlinić, Dinko, Rose, William A., Leifer, Cynthia A., Bendelja, Kreso, Gabrilovac, Jelka, Parcina, Marijo, Lauc, Gordan, Kubarenko, Andriy V., Petricevic, Branka, Vrbanec, Damir, Bulat-Kardum, Ljiljana, Bekeredjian-Ding, Isabelle, Pavelić, Jasminka, Dembić, Zlatko, Weber, Alexander N. R.
Publicado em 2012

A Coding IRAK2 Protein Variant Compromises Toll-like receptor (TLR) Signaling and Is Associated with Colorectal Cancer Survival

Por Wang, Hui, Flannery, Sinead M., Dickhöfer, Sabine, Huhn, Stefanie, George, Julie, Kubarenko, Andriy V., Lascorz, Jesus, Bevier, Melanie, Willemsen, Joschka, Pichulik, Tica, Schafmayer, Clemens, Binder, Marco, Manoury, Bénédicte, Paludan, Søren R., Alarcon-Riquelme, Marta, Bowie, Andrew G., Försti, Asta, Weber, Alexander N. R.
Publicado em 2014

RNA and Imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events

Por Colak, Elif, Leslie, Alasdair, Zausmer, Kieran, Khatamzas, Elham, Kubarenko, Andriy V., Pichulik, Tica, Klimosch, Sascha N., Mayer, Alice, Siggs, Owen, Hector, Andreas, Fischer, Roman, Klesser, Benedikt, Rautanen, Anna, Frank, Martin, Hill, Adrian V. S., Manoury, Bénédicte, Beutler, Bruce, Hartl, Dominik, Simmons, Alison, Weber, Alexander N. R.
Publicado em 2014

HLA class I-restricted MYD88 L265P-derived peptides as specific targets for lymphoma immunotherapy

Por Nelde, Annika, Walz, Juliane Sarah, Kowalewski, Daniel Johannes, Schuster, Heiko, Wolz, Olaf-Oliver, Peper, Janet Kerstin, Cardona Gloria, Yamel, Langerak, Anton W., Muggen, Alice F., Claus, Rainer, Bonzheim, Irina, Fend, Falko, Salih, Helmut Rainer, Kanz, Lothar, Rammensee, Hans-Georg, Stevanović, Stefan, Weber, Alexander N. R.
Publicado no Oncoimmunology (2016)

Pathogenic Fungi Regulate Immunity by Inducing Neutrophilic Myeloid-Derived Suppressor Cells

Por Rieber, Nikolaus, Singh, Anurag, Öz, Hasan, Carevic, Melanie, Bouzani, Maria, Amich, Jorge, Ost, Michael, Ye, Zhiyong, Ballbach, Marlene, Schäfer, Iris, Mezger, Markus, Klimosch, Sascha N., Weber, Alexander N.R., Handgretinger, Rupert, Krappmann, Sven, Liese, Johannes, Engeholm, Maik, Schüle, Rebecca, Salih, Helmut Rainer, Marodi, Laszlo, Speckmann, Carsten, Grimbacher, Bodo, Ruland, Jürgen, Brown, Gordon D., Beilhack, Andreas, Loeffler, Juergen, Hartl, Dominik
Publicado no Cell Host Microbe (2015)

B-cell–specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B-cell lymphoma in mice

Por Knittel, Gero, Liedgens, Paul, Korovkina, Darya, Seeger, Jens M., Al-Baldawi, Yussor, Al-Maarri, Mona, Fritz, Christian, Vlantis, Katerina, Bezhanova, Svetlana, Scheel, Andreas H., Wolz, Olaf-Oliver, Reimann, Maurice, Möller, Peter, López, Cristina, Schlesner, Matthias, Lohneis, Philipp, Weber, Alexander N. R., Trümper, Lorenz, Staudt, Louis M., Ortmann, Monika, Pasparakis, Manolis, Siebert, Reiner, Schmitt, Clemens A., Klatt, Andreas R., Wunderlich, F. Thomas, Schäfer, Stephan C., Persigehl, Thorsten, Montesinos-Rongen, Manuel, Odenthal, Margarete, Büttner, Reinhard, Frenzel, Lukas P., Kashkar, Hamid, Reinhardt, H. Christian
Publicado no Blood (2016)