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Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA

Genetic evidence indicates that Drosophila defense against Gram-positive bacteria is mediated by two putative pattern recognition receptors acting upstream of Toll, namely Gram-negative binding protein 1 (GNBP1) and peptidoglycan recognition protein SA (PGRP-SA). Until now however, the molecular rec...

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Detalhes bibliográficos
Main Authors: Wang, Lihui, Weber, Alexander N R, Atilano, Magda L, Filipe, Sergio R, Gay, Nicholas J, Ligoxygakis, Petros
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618108/
https://ncbi.nlm.nih.gov/pubmed/17024181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601363
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