Pharmacokinetics and Pharmacodynamics of a Novel Triazole, Isavuconazole: Mathematical Modeling, Importance of Tissue Concentrations, and Impact of Immune Status on Antifungal Effe...

Por Warn, Peter A., Sharp, Andrew, Parmar, Arvind, Majithiya, Jayesh, Denning, David W., Hope, William W.
Publicado em 2009

Combination of Voriconazole and Anidulafungin for Treatment of Triazole-Resistant Aspergillus fumigatus in an In Vitro Model of Invasive Pulmonary Aspergillosis

Por Jeans, Adam R., Howard, Susan J., Al-Nakeeb, Zaid, Goodwin, Joanne, Gregson, Lea, Warn, Peter A., Hope, William W.
Publicado em 2012

Interrogation of Related Clinical Pan-Azole-Resistant Aspergillus fumigatus Strains: G138C, Y431C, and G434C Single Nucleotide Polymorphisms in cyp51A, Upregulation of cyp51A, and...

Por Albarrag, Ahmed M., Anderson, Michael J., Howard, Susan J., Robson, Geoff D., Warn, Peter A., Sanglard, Dominique, Denning, David W.
Publicado em 2011

Effect of Neutropenia and Treatment Delay on the Response to Antifungal Agents in Experimental Disseminated Candidiasis

Por Hope, William W., Drusano, George L., Moore, Caroline B., Sharp, Andrew, Louie, Arnold, Walsh, Thomas J., Denning, David W., Warn, Peter A.
Publicado em 2007

Pharmacodynamics of Echinocandins against Candida glabrata: Requirement for Dosage Escalation To Achieve Maximal Antifungal Activity in Neutropenic Hosts

Por Howard, Susan J., Livermore, Joanne, Sharp, Andrew, Goodwin, Joanne, Gregson, Lea, Alastruey-Izquierdo, A., Perlin, D. S., Warn, Peter A., Hope, William W.
Publicado em 2011

Derivation of an In Vivo Drug Exposure Breakpoint for Flucytosine against Candida albicans and Impact of the MIC, Growth Rate, and Resistance Genotype on the Antifungal Effect

Por Hope, William W., Warn, Peter A., Sharp, Andrew, Howard, Susan, Kasai, Miki, Louie, Arnold, Walsh, Thomas J., Drusano, George L., Denning, David W.
Publicado em 2006

Optimization of the Dosage of Flucytosine in Combination with Amphotericin B for Disseminated Candidiasis: a Pharmacodynamic Rationale for Reduced Dosing

Por Hope, William W., Warn, Peter A., Sharp, Andrew, Reed, Paul, Keevil, Brian, Louie, Arnold, Walsh, Thomas J., Denning, David W., Drusano, George L.
Publicado em 2007

Pharmacokinetics and Pharmacodynamics of Posaconazole for Invasive Pulmonary Aspergillosis: Clinical Implications for Antifungal Therapy

Por Howard, Susan J., Lestner, Jodi M., Sharp, Andrew, Gregson, Lea, Goodwin, Joanne, Slater, Joanne, Majithiya, Jayesh B., Warn, Peter A., Hope, William W.
Publicado em 2011

In Vivo Targeting of Escherichia coli with Vancomycin-Arginine

Por Neville, Lewis F., Shalit, Itamar, Warn, Peter A., Scheetz, Marc H., Sun, Jiuzhi, Chosy, Madeline B., Wender, Paul A., Cegelski, Lynette, Rendell, Jacob T.
Publicado no Antimicrob Agents Chemother (2021)

The Aspergillus fumigatus Dihydroxyacid Dehydratase Ilv3A/IlvC Is Required for Full Virulence

Por Oliver, Jason D., Kaye, Sarah J., Tuckwell, Danny, Johns, Anna E., Macdonald, Darel A., Livermore, Joanne, Warn, Peter A., Birch, Mike, Bromley, Michael J.
Publicado em 2012

Pharmacodynamics of Itraconazole against Aspergillus fumigatus in an In Vitro Model of the Human Alveolus: Perspectives on the Treatment of Triazole-Resistant Infection and Utility...

Por Al-Nakeeb, Zaid, Sudan, Ajay, Jeans, Adam R., Gregson, Lea, Goodwin, Joanne, Warn, Peter A., Felton, Timothy W., Howard, Susan J., Hope, William W.
Publicado em 2012

Pharmacokinetics and Pharmacodynamics of Fluconazole for Cryptococcal Meningoencephalitis: Implications for Antifungal Therapy and In Vitro Susceptibility Breakpoints

Por Sudan, Ajay, Livermore, Joanne, Howard, Susan J., Al-Nakeeb, Zaid, Sharp, Andrew, Goodwin, Joanne, Gregson, Lea, Warn, Peter A., Felton, Tim W., Perfect, John R., Harrison, Thomas S., Hope, William W.
Publicado em 2013

Anidulafungin for Neonatal Hematogenous Candida Meningoencephalitis: Identification of Candidate Regimens for Humans Using a Translational Pharmacological Approach

Por Warn, Peter A., Livermore, Joanne, Howard, Susan, Felton, Timothy W., Sharp, Andrew, Gregson, Lea, Goodwin, Joanne, Petraitiene, Ruta, Petraitis, Vidmantas, Cohen-Wolkowiez, Michael, Walsh, Thomas J., Benjamin, Daniel K., Hope, William W.
Publicado em 2012

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

Por d'Enfert, Christophe, Kaune, Ann-Kristin, Alaban, Leovigildo-Rey, Chakraborty, Sayoni, Cole, Nathaniel, Delavy, Margot, Kosmala, Daria, Marsaux, Benoît, Fróis-Martins, Ricardo, Morelli, Moran, Rosati, Diletta, Valentine, Marisa, Xie, Zixuan, Emritloll, Yoan, Warn, Peter A, Bequet, Frédéric, Bougnoux, Marie-Elisabeth, Bornes, Stephanie, Gresnigt, Mark S, Hube, Bernhard, Jacobsen, Ilse D, Legrand, Mélanie, Leibundgut-Landmann, Salomé, Manichanh, Chaysavanh, Munro, Carol A, Netea, Mihai G, Queiroz, Karla, Roget, Karine, Thomas, Vincent, Thoral, Claudia, Van den Abbeele, Pieter, Walker, Alan W, Brown, Alistair J P
Publicado no FEMS Microbiol Rev (2020)