Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection

Por Damen, Carola W. N., Isaac, Giorgis, Langridge, James, Hankemeier, Thomas, Vreeken, Rob J.
Publicado em 2014

Fragmentation trees for the structural characterisation of metabolites

Por Kasper, Piotr T, Rojas-Chertó, Miguel, Mistrik, Robert, Reijmers, Theo, Hankemeier, Thomas, Vreeken, Rob J
Publicado em 2012

Development and application of a UHPLC–MS/MS metabolomics based comprehensive systemic and tissue-specific screening method for inflammatory, oxidative and nitrosative stress

Por Schoeman, Johannes C., Harms, Amy C., van Weeghel, Michel, Berger, Ruud, Vreeken, Rob J., Hankemeier, Thomas
Publicado no Anal Bioanal Chem (2018)

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery

Por van Smeden, Jeroen, Hoppel, Louise, van der Heijden, Rob, Hankemeier, Thomas, Vreeken, Rob J., Bouwstra, Joke A.
Publicado em 2011

Metabolic characterization of the natural progression of chronic hepatitis B

Por Schoeman, Johannes C., Hou, Jun, Harms, Amy C., Vreeken, Rob J., Berger, Ruud, Hankemeier, Thomas, Boonstra, Andre
Publicado no Genome Med (2016)

Direct nose to brain delivery of small molecules: critical analysis of data from a standardized in vivo screening model in rats

Por Dhuyvetter, Deborah, Tekle, Fetene, Nazarov, Maxim, Vreeken, Rob J., Borghys, Herman, Rombouts, Frederik, Lenaerts, Ilse, Bottelbergs, Astrid
Publicado no Drug Deliv (2020)

Mass Spectrometric Analysis of Intact Human Monoclonal Antibody Aggregates Fractionated by Size-Exclusion Chromatography

Por Kükrer, Başak, Filipe, Vasco, van Duijn, Esther, Kasper, Piotr T., Vreeken, Rob J., Heck, Albert J. R., Jiskoot, Wim
Publicado em 2010

Spatial heterogeneity of nanomedicine investigated by multiscale imaging of the drug, the nanoparticle and the tumour environment

Por de Maar, Josanne Sophia, Sofias, Alexandros Marios, Porta Siegel, Tiffany, Vreeken, Rob J., Moonen, Chrit, Bos, Clemens, Deckers, Roel
Publicado no Theranostics (2020)

Serum-Based Oxylipins Are Associated with Outcomes in Primary Prevention Implantable Cardioverter Defibrillator Patients

Por Zhang, Yiyi, Guallar, Eliseo, Blasco-Colmenares, Elena, Harms, Amy C., Vreeken, Rob J., Hankemeier, Thomas, Tomaselli, Gordon F., Cheng, Alan
Publicado no PLoS One (2016)

Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets

Por Bruins, Maaike J., Dane, Adrie D., Strassburg, Katrin, Vreeken, Rob J., Newman, John W., Salem, Norman, Tyburczy, Cynthia, Brenna, J. Thomas
Publicado em 2013

Novel Key Metabolites Reveal Further Branching of the Roquefortine/Meleagrin Biosynthetic Pathway

Por Ries, Marco I., Ali, Hazrat, Lankhorst, Peter P., Hankemeier, Thomas, Bovenberg, Roel A. L., Driessen, Arnold J. M., Vreeken, Rob J.
Publicado em 2013

Genomic mutational analysis of the impact of the classical strain improvement program on β–lactam producing Penicillium chrysogenum

Por Salo, Oleksandr V., Ries, Marco, Medema, Marnix H., Lankhorst, Peter P., Vreeken, Rob J., Bovenberg, Roel A. L., Driessen, Arnold J. M.
Publicado no BMC Genomics (2015)

Identification of a Polyketide Synthase Involved in Sorbicillin Biosynthesis by Penicillium chrysogenum

Por Salo, Oleksandr, Guzmán-Chávez, Fernando, Ries, Marco I., Lankhorst, Peter P., Bovenberg, Roel A. L., Vreeken, Rob J., Driessen, Arnold J. M.
Publicado no Appl Environ Microbiol (2016)

Deregulation of secondary metabolism in a histone deacetylase mutant of Penicillium chrysogenum

Por Guzman‐Chavez, Fernando, Salo, Oleksandr, Samol, Marta, Ries, Marco, Kuipers, Jeroen, Bovenberg, Roel A. L., Vreeken, Rob J., Driessen, Arnold J. M.
Publicado no Microbiologyopen (2018)

Metabolic Phenotyping Reveals a Lipid Mediator Response to Ionizing Radiation

Por Laiakis, Evagelia C., Strassburg, Katrin, Bogumil, Ralf, Lai, Steven, Vreeken, Rob J., Hankemeier, Thomas, Langridge, James, Plumb, Robert S., Fornace, Albert J., Astarita, Giuseppe
Publicado em 2014

Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry

Por Lamont, Lieke, Eijkel, Gert B., Jones, Emrys A., Flinders, Bryn, Ellis, Shane R., Porta Siegel, Tiffany, Heeren, Ron M.A., Vreeken, Rob J.
Publicado no Anal Chem (2018)

A Branched Biosynthetic Pathway Is Involved in Production of Roquefortine and Related Compounds in Penicillium chrysogenum

Por Ali, Hazrat, Ries, Marco I., Nijland, Jeroen G., Lankhorst, Peter P., Hankemeier, Thomas, Bovenberg, Roel A. L., Vreeken, Rob J., Driessen, Arnold J. M.
Publicado em 2013

Lipidomics of familial longevity

Por Gonzalez-Covarrubias, Vanessa, Beekman, Marian, Uh, Hae-Won, Dane, Adrie, Troost, Jorne, Paliukhovich, Iryna, Kloet, Frans M, Houwing-Duistermaat, Jeanine, Vreeken, Rob J, Hankemeier, Thomas, Slagboom, Eline P
Publicado em 2013

A Protective Lipidomic Biosignature Associated with a Balanced Omega-6/Omega-3 Ratio in fat-1 Transgenic Mice

Por Astarita, Giuseppe, McKenzie, Jennifer H., Wang, Bin, Strassburg, Katrin, Doneanu, Angela, Johnson, Jay, Baker, Andrew, Hankemeier, Thomas, Murphy, James, Vreeken, Rob J., Langridge, James, Kang, Jing X.
Publicado em 2014

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients

Por Janssens, Michelle, van Smeden, Jeroen, Gooris, Gert S., Bras, Wim, Portale, Guiseppe, Caspers, Peter J., Vreeken, Rob J., Hankemeier, Thomas, Kezic, Sanja, Wolterbeek, Ron, Lavrijsen, Adriana P., Bouwstra, Joke A.
Publicado em 2012