Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry

[Image: see text] Mass spectrometry imaging (MSI) has proven to be a valuable tool for drug and metabolite imaging in pharmaceutical toxicology studies and can reveal, for example, accumulation of drug candidates in early drug development. However, the lack of sample cleanup and chromatographic sepa...

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發表在:Anal Chem
Main Authors: Lamont, Lieke, Eijkel, Gert B., Jones, Emrys A., Flinders, Bryn, Ellis, Shane R., Porta Siegel, Tiffany, Heeren, Ron M.A., Vreeken, Rob J.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2018
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256344/
https://ncbi.nlm.nih.gov/pubmed/30346139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b03857
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