Uncovering Ubiquitin and Ubiquitin-like Signaling Networks

Por Vertegaal, Alfred C. O.
Publicado em 2011

Mapping the SUMOylated landscape

Por Eifler, Karolin, Vertegaal, Alfred C.O.
Publicado no FEBS J (2015)

SUMOylation-mediated regulation of cell cycle progression and cancer

Por Eifler, Karolin, Vertegaal, Alfred C.O.
Publicado no Trends Biochem Sci (2015)

Ubiquitin-dependent and independent roles of SUMO in proteostasis

Por Liebelt, Frauke, Vertegaal, Alfred C. O.
Publicado no Am J Physiol Cell Physiol (2016)

SUMO in the DNA damage response

Por Hendriks, Ivo A., Vertegaal, Alfred C.O.
Publicado no Oncotarget (2015)

Converging Small Ubiquitin-like Modifier (SUMO) and Ubiquitin Signaling: Improved Methodology Identifies Co-modified Target Proteins

Por Cuijpers, Sabine A. G., Willemstein, Edwin, Vertegaal, Alfred C. O.
Publicado no Mol Cell Proteomics (2017)

Chemical Tools and Biochemical Assays for SUMO Specific Proteases (SENPs)

Por Jia, Yuqing, Claessens, Laura A., Vertegaal, Alfred C. O., Ovaa, Huib
Publicado no ACS Chem Biol (2019)

RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2α

Por van Hagen, Martijn, Overmeer, René M., Abolvardi, Sharareh S., Vertegaal, Alfred C. O.
Publicado em 2010

Ubiquitin-specific Protease 11 (USP11) Deubiquitinates Hybrid Small Ubiquitin-like Modifier (SUMO)-Ubiquitin Chains to Counteract RING Finger Protein 4 (RNF4)

Por Hendriks, Ivo A., Schimmel, Joost, Eifler, Karolin, Olsen, Jesper V., Vertegaal, Alfred C. O.
Publicado no J Biol Chem (2015)

Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies

Por Sha, Zhe, Blyszcz, Tamara, González-Prieto, Román, Vertegaal, Alfred C. O., Goldberg, Alfred L.
Publicado no J Biol Chem (2019)

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

Por Kumar, Ramesh, González-Prieto, Román, Xiao, Zhenyu, Verlaan-de Vries, Matty, Vertegaal, Alfred C. O.
Publicado no Nat Commun (2017)

System-wide identification of wild-type SUMO-2 conjugation sites

Por Hendriks, Ivo A., D'Souza, Rochelle C., Chang, Jer-Gung, Mann, Matthias, Vertegaal, Alfred C. O.
Publicado no Nat Commun (2015)

SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage

Por Hendriks, Ivo A., Treffers, Louise W., Verlaan - de Vries, Matty, Olsen, Jesper V., Vertegaal, Alfred C.O.
Publicado no Cell Rep (2015)

System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome...

Por Xiao, Zhenyu, Chang, Jer-Gung, Hendriks, Ivo A., Sigurðsson, Jón Otti, Olsen, Jesper V., Vertegaal, Alfred C.O.
Publicado no Mol Cell Proteomics (2015)

Telomeric DNA Mediates De Novo PML Body Formation

Por Brouwer, Anneke K., Schimmel, Joost, Wiegant, Joop C.A.G., Vertegaal, Alfred C.O., Tanke, Hans J., Dirks, Roeland W.
Publicado em 2009

Uncovering Global SUMOylation Signaling Networks in a Site-Specific Manner

Por Hendriks, Ivo A., D’Souza, Rochelle C.J., Yang, Bing, Verlaan-de Vries, Matty, Mann, Matthias, Vertegaal, Alfred C.O.
Publicado no Nat Struct Mol Biol (2014)

The N and C Termini of the Splice Variants of the Human Mitogen-Activated Protein Kinase-Interacting Kinase Mnk2 Determine Activity and Localization

Por Scheper, Gert C., Parra, Josep L., Wilson, Mary, van Kollenburg, Barbara, Vertegaal, Alfred C. O., Han, Ze-Guang, Proud, Christopher G.
Publicado em 2003

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock

Por Liebelt, Frauke, Sebastian, Rebecca M., Moore, Christopher L., Mulder, Monique P.C., Ovaa, Huib, Shoulders, Matthew D., Vertegaal, Alfred C.O.
Publicado no Cell Rep (2019)

The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation

Por Liebelt, Frauke, Jansen, Nicolette S., Kumar, Sumit, Gracheva, Ekaterina, Claessens, Laura A., Verlaan-de Vries, Matty, Willemstein, Edwin, Vertegaal, Alfred C. O.
Publicado no Nat Commun (2019)

SUMO targets the APC/C to regulate transition from metaphase to anaphase

Por Eifler, Karolin, Cuijpers, Sabine A. G., Willemstein, Edwin, Raaijmakers, Jonne A., El Atmioui, Dris, Ovaa, Huib, Medema, René H., Vertegaal, Alfred C. O.
Publicado no Nat Commun (2018)