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System-wide identification of wild-type SUMO-2 conjugation sites

SUMOylation is a reversible post-translational modification (PTM) regulating all nuclear processes. Identification of SUMOylation sites by mass spectrometry (MS) has been hampered by bulky tryptic fragments, which thus far necessitated the use of mutated SUMO. Here we present a SUMO-specific proteas...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Hendriks, Ivo A., D'Souza, Rochelle C., Chang, Jer-Gung, Mann, Matthias, Vertegaal, Alfred C. O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Pub. Group 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490555/
https://ncbi.nlm.nih.gov/pubmed/26073453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8289
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