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System-wide identification of wild-type SUMO-2 conjugation sites

SUMOylation is a reversible post-translational modification (PTM) regulating all nuclear processes. Identification of SUMOylation sites by mass spectrometry (MS) has been hampered by bulky tryptic fragments, which thus far necessitated the use of mutated SUMO. Here we present a SUMO-specific proteas...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Hendriks, Ivo A., D'Souza, Rochelle C., Chang, Jer-Gung, Mann, Matthias, Vertegaal, Alfred C. O.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490555/
https://ncbi.nlm.nih.gov/pubmed/26073453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8289
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