System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability

Genotoxic agents can cause replication fork stalling in dividing cells because of DNA lesions, eventually leading to replication fork collapse when the damage is not repaired. Small Ubiquitin-like Modifiers (SUMOs) are known to counteract replication stress, nevertheless, only a small number of rele...

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Publicado no:Mol Cell Proteomics
Main Authors: Xiao, Zhenyu, Chang, Jer-Gung, Hendriks, Ivo A., Sigurðsson, Jón Otti, Olsen, Jesper V., Vertegaal, Alfred C.O.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Technological Innovation and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424410/
https://ncbi.nlm.nih.gov/pubmed/25755297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.044792
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