System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability

Genotoxic agents can cause replication fork stalling in dividing cells because of DNA lesions, eventually leading to replication fork collapse when the damage is not repaired. Small Ubiquitin-like Modifiers (SUMOs) are known to counteract replication stress, nevertheless, only a small number of rele...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Xiao, Zhenyu, Chang, Jer-Gung, Hendriks, Ivo A., Sigurðsson, Jón Otti, Olsen, Jesper V., Vertegaal, Alfred C.O.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2015
Subjects:
Technological Innovation and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424410/
https://ncbi.nlm.nih.gov/pubmed/25755297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.044792
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