Načítá se...

Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies

Protein ubiquitination and SUMOylation are required for the maintenance of cellular protein homeostasis, and both increase in proteotoxic conditions (e.g. heat shock or proteasome inhibition). However, we found that when ubiquitination was blocked in several human cell lines by inhibiting the ubiqui...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Sha, Zhe, Blyszcz, Tamara, González-Prieto, Román, Vertegaal, Alfred C. O., Goldberg, Alfred L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802522/
https://ncbi.nlm.nih.gov/pubmed/31285264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009147
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!