Unlocking ATP13A2/PARK9 activity

Por Martin, Shaun, Holemans, Tine, Vangheluwe, Peter
Publicado no Cell Cycle (2015)

Modeling Ca(2+) Dynamics of Mouse Cardiac Cells Points to a Critical Role of SERCA's Affinity for Ca(2+)

Por Raeymaekers, Luc, Vandecaetsbeek, Ilse, Wuytack, Frank, Vangheluwe, Peter
Publicado em 2011

Regulation of endoplasmic reticulum Ca(2+) oscillations in mammalian eggs

Por Wakai, Takuya, Zhang, Nan, Vangheluwe, Peter, Fissore, Rafael A.
Publicado em 2013

The Ca(2+) Pumps of the Endoplasmic Reticulum and Golgi Apparatus

Por Vandecaetsbeek, Ilse, Vangheluwe, Peter, Raeymaekers, Luc, Wuytack, Frank, Vanoevelen, Jo
Publicado em 2011

Sarco(endo)plasmic Reticulum Calcium ATPase (SERCA) Inhibition by Sarcolipin Is Encoded in Its Luminal Tail

Por Gorski, Przemek A., Glaves, John Paul, Vangheluwe, Peter, Young, Howard S.
Publicado em 2013

Sarcolipin and phospholamban mRNA and protein expression in cardiac and skeletal muscle of different species

Por Vangheluwe, Peter, Schuermans, Marleen, Zádor, Ernö, Waelkens, Etienne, Raeymaekers, Luc, Wuytack, Frank
Publicado em 2005

Distinct Roles of the C-terminal 11th Transmembrane Helix and Luminal Extension in the Partial Reactions Determining the High Ca(2+) Affinity of Sarco(endo)plasmic Reticulum Ca(2+)...

Por Clausen, Johannes D., Vandecaetsbeek, Ilse, Wuytack, Frank, Vangheluwe, Peter, Andersen, Jens Peter
Publicado em 2012

Transmembrane Helix 11 Is a Genuine Regulator of the Endoplasmic Reticulum Ca(2+) Pump and Acts as a Functional Parallel of β-Subunit on α-Na(+),K(+)-ATPase

Por Gorski, Przemek A., Trieber, Catharine A., Larivière, Els, Schuermans, Marleen, Wuytack, Frank, Young, Howard S., Vangheluwe, Peter
Publicado em 2012

Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders

Por van Veen, Sarah, Sørensen, Danny M., Holemans, Tine, Holen, Henrik W., Palmgren, Michael G., Vangheluwe, Peter
Publicado em 2014

Structural basis for the high Ca(2+) affinity of the ubiquitous SERCA2b Ca(2+) pump

Por Vandecaetsbeek, Ilse, Trekels, Mieke, De Maeyer, Marc, Ceulemans, Hugo, Lescrinier, Eveline, Raeymaekers, Luc, Wuytack, Frank, Vangheluwe, Peter
Publicado em 2009

The Ca(2+)-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy

Por Kecskés, Miklós, Jacobs, Griet, Kerselaers, Sara, Syam, Ninda, Menigoz, Aurélie, Vangheluwe, Peter, Freichel, Marc, Flockerzi, Veit, Voets, Thomas, Vennekens, Rudi
Publicado no Basic Res Cardiol (2015)

Ca(2+) Induces Spontaneous Dephosphorylation of a Novel P5A-type ATPase

Por Sørensen, Danny Mollerup, Møller, Annette B., Jakobsen, Mia K., Jensen, Michael K., Vangheluwe, Peter, Buch-Pedersen, Morten J., Palmgren, Michael G.
Publicado em 2012

Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2

Por Martin, Shaun, van Veen, Sarah, Holemans, Tine, Demirsoy, Seyma, van den Haute, Chris, Baekelandt, Veerle, Agostinis, Patrizia, Eggermont, Jan, Vangheluwe, Peter
Publicado no Parkinsons Dis (2016)

Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin-free skeletal muscle

Por Ottenheijm, Coen A. C., Fong, Chi, Vangheluwe, Peter, Wuytack, Frank, Babu, Gopal J., Periasamy, Muthu, Witt, Christian C., Labeit, Siegfried, Granzier, Henk
Publicado em 2008

A lipid switch unlocks Parkinson’s disease-associated ATP13A2

Por Holemans, Tine, Sørensen, Danny Mollerup, van Veen, Sarah, Martin, Shaun, Hermans, Diane, Kemmer, Gerdi Christine, Van den Haute, Chris, Baekelandt, Veerle, Günther Pomorski, Thomas, Agostinis, Patrizia, Wuytack, Frank, Palmgren, Michael, Eggermont, Jan, Vangheluwe, Peter
Publicado no Proc Natl Acad Sci U S A (2015)

A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency

Por Tharkeshwar, Arun Kumar, Trekker, Jesse, Vermeire, Wendy, Pauwels, Jarne, Sannerud, Ragna, Priestman, David A., te Vruchte, Danielle, Vints, Katlijn, Baatsen, Pieter, Decuypere, Jean-Paul, Lu, Huiqi, Martin, Shaun, Vangheluwe, Peter, Swinnen, Johannes V., Lagae, Liesbet, Impens, Francis, Platt, Frances M., Gevaert, Kris, Annaert, Wim
Publicado no Sci Rep (2017)

Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)

Por Estrada-Cuzcano, Alejandro, Martin, Shaun, Chamova, Teodora, Synofzik, Matthis, Timmann, Dagmar, Holemans, Tine, Andreeva, Albena, Reichbauer, Jennifer, De Rycke, Riet, Chang, Dae-In, van Veen, Sarah, Samuel, Jean, Schöls, Ludger, Pöppel, Thorsten, Mollerup Sørensen, Danny, Asselbergh, Bob, Klein, Christine, Zuchner, Stephan, Jordanova, Albena, Vangheluwe, Peter, Tournev, Ivailo, Schüle, Rebecca
Publicado no Brain (2017)