Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders

Mutations in ATP13A2 lead to Kufor-Rakeb syndrome, a parkinsonism with dementia. ATP13A2 belongs to the P-type transport ATPases, a large family of primary active transporters that exert vital cellular functions. However, the cellular function and transported substrate of ATP13A2 remain unknown. To...

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Detalhes bibliográficos
Main Authors: van Veen, Sarah, Sørensen, Danny M., Holemans, Tine, Holen, Henrik W., Palmgren, Michael G., Vangheluwe, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033846/
https://ncbi.nlm.nih.gov/pubmed/24904274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00048
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