Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation

Por Valerius, M. Todd, McMahon, Andrew P.
Publicado em 2008

Hoxa 11 is upstream of Integrin α8 expression in the developing kidney

Por Valerius, M. Todd, Patterson, Larry T., Feng, Yuxin, Potter, S. Steven
Publicado em 2002

Orphan Nuclear Receptor Nur77 Promotes Acute Kidney Injury and Renal Epithelial Apoptosis

Por Balasubramanian, Savithri, Jansen, Marcel, Valerius, M. Todd, Humphreys, Benjamin D., Strom, Terry B.
Publicado em 2012

Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells

Por Boyle, Scott C., Kim, Mijin, Valerius, M. Todd, McMahon, Andrew P., Kopan, Raphael
Publicado em 2011

Node retraction during patterning of the urinary collecting duct system

Por Lindström, Nils O, Chang, C-Hong, Valerius, M Todd, Hohenstein, Peter, Davies, Jamie A
Publicado no J Anat (2015)

Repair after nephron ablation reveals limitations of neonatal neonephrogenesis

Por Tögel, Florian, Valerius, M. Todd, Freedman, Benjamin S., Iatrino, Rossella, Grinstein, Mor, Bonventre, Joseph V.
Publicado no JCI Insight (2017)

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

Por Morizane, Ryuji, Lam, Albert Q., Freedman, Benjamin S., Kishi, Seiji, Valerius, M. Todd, Bonventre, Joseph V.
Publicado no Nat Biotechnol (2015)

Rapid and Efficient Differentiation of Human Pluripotent Stem Cells into Intermediate Mesoderm That Forms Tubules Expressing Kidney Proximal Tubular Markers

Por Lam, Albert Q., Freedman, Benjamin S., Morizane, Ryuji, Lerou, Paul H., Valerius, M. Todd, Bonventre, Joseph V.
Publicado em 2014

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney

Por Nagalakshmi, Vidya K., Ren, Qun, Pugh, Margaret M., Valerius, M. Todd, McMahon, Andrew P., Yu, Jing
Publicado em 2010

SOCS2 Balances Metabolic and Restorative Requirements during Liver Regeneration

Por Masuzaki, Ryota, Zhao, Sophia, Valerius, M. Todd, Tsugawa, Daisuke, Oya, Yuki, Ray, Kevin C., Karp, Seth J.
Publicado no J Biol Chem (2016)

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

Por Kobayashi, Akio, Valerius, M. Todd, Mugford, Joshua W., Carroll, Thomas J., Self, Michelle, Oliver, Guillermo, McMahon, Andrew P.
Publicado em 2008

Notch2 (but not Notch1) is required for proximal fate acquisition in the mammalian nephron

Por Cheng, Hui-Teng, Kim, Mijin, Valerius, M Todd, Surendran, Kameswaran, Schuster-Gossler, Karin, Gossler, Achim, McMahon, Andrew P., Kopan, Raphael
Publicado em 2007

IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease

Por Baek, Jea-Hyun, Zeng, Rui, Weinmann-Menke, Julia, Valerius, M. Todd, Wada, Yukihiro, Ajay, Amrendra K., Colonna, Marco, Kelley, Vicki R.
Publicado no J Clin Invest (2015)

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

Por Humphreys, Benjamin D., Lin, Shuei-Liong, Kobayashi, Akio, Hudson, Thomas E., Nowlin, Brian T., Bonventre, Joseph V., Valerius, M. Todd, McMahon, Andrew P., Duffield, Jeremy S.
Publicado em 2010

Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks

Por Park, Joo-Seop, Ma, Wenxiu, O’Brien, Lori L., Chung, Eunah, Guo, Jin-Jin, Cheng, Jr-Gang, Valerius, M. Todd, McMahon, Jill A., Wong, Wing Hung, McMahon, Andrew P.
Publicado em 2012

Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution

Por Brunskill, Eric W., Aronow, Bruce J., Georgas, Kylie, Rumballe, Bree, Valerius, M. Todd, Aronow, Jeremy, Kaimal, Vivek, Jegga, Anil G., Grimmond, Sean, McMahon, Andrew P., Patterson, Larry T., Little, Melissa H., Potter, S. Steven
Publicado em 2008

A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract

Por Wiese, Carrie B., Ireland, Sara, Fleming, Nicole L., Yu, Jing, Valerius, M. Todd, Georgas, Kylie, Chiu, Han Sheng, Brennan, Jane, Armstrong, Jane, Little, Melissa H., McMahon, Andrew P., Southard-Smith, E. Michelle
Publicado em 2012

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

Por Freedman, Benjamin S., Brooks, Craig R., Lam, Albert Q., Fu, Hongxia, Morizane, Ryuji, Agrawal, Vishesh, Saad, Abdelaziz F., Li, Michelle K., Hughes, Michael R., Werff, Ryan Vander, Peters, Derek T., Lu, Junjie, Baccei, Anna, Siedlecki, Andrew M., Valerius, M. Todd, Musunuru, Kiran, McNagny, Kelly M., Steinman, Theodore I., Zhou, Jing, Lerou, Paul H., Bonventre, Joseph V.
Publicado no Nat Commun (2015)

Identification of molecular compartments and genetic circuitry in the developing mammalian kidney

Por Yu, Jing, Valerius, M. Todd, Duah, Mary, Staser, Karl, Hansard, Jennifer K., Guo, Jin-jin, McMahon, Jill, Vaughan, Joe, Faria, Diane, Georgas, Kylie, Rumballe, Bree, Ren, Qun, Krautzberger, A. Michaela, Junker, Jan P., Thiagarajan, Rathi D., Machanick, Philip, Gray, Paul A., van Oudenaarden, Alexander, Rowitch, David H., Stiles, Charles D., Ma, Qiufu, Grimmond, Sean M., Bailey, Timothy L., Little, Melissa H., McMahon, Andrew P.
Publicado em 2012

A high-resolution anatomical ontology of the developing murine genitourinary tract

Por Little, Melissa H., Brennan, Jane, Georgas, Kylie, Davies, Jamie A., Davidson, Duncan R., Baldock, Richard A., Beverdam, Annemiek, Bertram, John F., Capel, Blanche, Chiu, Han Sheng, Clements, Dave, Cullen-McEwen, Luise, Fleming, Jean, Gilbert, Thierry, Houghton, Derek, Kaufman, Matt H., Kleymenova, Elena, Koopman, Peter A., Lewis, Alfor G., McMahon, Andrew P., Mendelsohn, Cathy L., Mitchell, Eleanor K., Rumballe, Bree A., Sweeney, Derina E., Valerius, M. Todd, Yamada, Gen, Yang, Yiya, Yu., Jing
Publicado em 2007