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Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks
A balance between Six2-dependent self-renewal and canonical Wnt signaling-directed commitment regulates mammalian nephrogenesis. Intersectional studies using chromatin immunoprecipitation and transcriptional profiling identified direct target genes shared by each pathway within nephron progenitors....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3892952/ https://ncbi.nlm.nih.gov/pubmed/22902740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.07.008 |
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