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Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells

The primary excretory organ in vertebrates is the kidney, which is responsible for blood filtration, solute homeostasis and pH balance. These functions are carried out by specialized epithelial cells organized into tubules called nephrons. Each of these cell types arise during embryonic development...

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Autori principali: Boyle, Scott C., Kim, Mijin, Valerius, M. Todd, McMahon, Andrew P., Kopan, Raphael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171224/
https://ncbi.nlm.nih.gov/pubmed/21852398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.070433
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