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Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development

Mesangial cells are specialized pericyte/smooth muscle cells that surround and constrain the vascular network within the glomerulus of the kidney. They are derived from the stromal mesenchyme, a progenitor population distinct from nephron stem cells. Whether mesangial cells have a distinct origin fr...

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Detalhes bibliográficos
Main Authors: Boyle, Scott C., Liu, Zhenyi, Kopan, Raphael
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074211/
https://ncbi.nlm.nih.gov/pubmed/24353058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.100271
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