Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

Understanding the origin of myofibroblasts in kidney is of great interest because these cells are responsible for scar formation in fibrotic kidney disease. Recent studies suggest epithelial cells are an important source of myofibroblasts through a process described as the epithelial-to-mesenchymal...

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Detalhes bibliográficos
Main Authors: Humphreys, Benjamin D., Lin, Shuei-Liong, Kobayashi, Akio, Hudson, Thomas E., Nowlin, Brian T., Bonventre, Joseph V., Valerius, M. Todd, McMahon, Andrew P., Duffield, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797872/
https://ncbi.nlm.nih.gov/pubmed/20008127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090517
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