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Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

Understanding the origin of scar-producing myofibroblasts is vital in discerning the mechanisms by which fibrosis develops in response to inflammatory injury. Using a transgenic reporter mouse model expressing enhanced green fluorescent protein (GFP) under the regulation of the collagen type I, α 1...

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Detalhes bibliográficos
Main Authors: Lin, Shuei-Liong, Kisseleva, Tatiana, Brenner, David A., Duffield, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626374/
https://ncbi.nlm.nih.gov/pubmed/19008372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080433
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