Transaminase Elevations during Treatment of Chronic Hepatitis B Infection: Safety Considerations and Role in Achieving Functional Cure

door Vaillant, Andrew
Gepubliceerd in Viruses (2021)

Nucleic Acid Polymers Prevent the Establishment of Duck Hepatitis B Virus Infection In Vivo

door Noordeen, Faseeha, Vaillant, Andrew, Jilbert, Allison R.
Gepubliceerd in 2013

Nucleic Acid Polymers Inhibit Duck Hepatitis B Virus Infection In Vitro

door Noordeen, Faseeha, Vaillant, Andrew, Jilbert, Allison R.
Gepubliceerd in 2013

Safety and Efficacy of Nucleic Acid Polymers in Monotherapy and Combined with Immunotherapy in Treatment-Naive Bangladeshi Patients with HBeAg+ Chronic Hepatitis B Infection

door Al-Mahtab, Mamun, Bazinet, Michel, Vaillant, Andrew
Gepubliceerd in PLoS One (2016)

Letter to the Editor: Examining HBV RNA kinetics during NA treatment - are NA multifunctional antiviral agents?

door Dahari, Harel, Vaillant, Andrew, Cotler, Scott J.
Gepubliceerd in Hepatology (2021)

Nucleic Acid Polymers Are Active against Hepatitis Delta Virus Infection In Vitro

door Beilstein, Frauke, Blanchet, Matthieu, Vaillant, Andrew, Sureau, Camille
Gepubliceerd in J Virol (2018)

Phosphorothioate Oligonucleotides Inhibit Human Immunodeficiency Virus Type 1 Fusion by Blocking gp41 Core Formation

door Vaillant, Andrew, Juteau, Jean-Marc, Lu, Hong, Liu, Shuwen, Lackman-Smith, Carol, Ptak, Roger, Jiang, Shibo
Gepubliceerd in 2006

Nucleic acid-based polymers effective against hepatitis B Virus infection in patients don’t harbor immunostimulatory properties in primary isolated liver cells

door Real, Catherine Isabell, Werner, Melanie, Paul, Andreas, Gerken, Guido, Schlaak, Joerg Friedrich, Vaillant, Andrew, Broering, Ruth
Gepubliceerd in Sci Rep (2017)

Nucleic acid polymer REP 2139 and nucleos(T)ide analogues act synergistically against chronic hepadnaviral infection in vivo in Pekin ducks

door Quinet, Jonathan, Jamard, Catherine, Burtin, Madeleine, Lemasson, Matthieu, Guerret, Sylviane, Sureau, Camille, Vaillant, Andrew, Cova, Lucyna
Gepubliceerd in Hepatology (2018)

Inhibition of Cellular Entry of Lymphocytic Choriomeningitis Virus by Amphipathic DNA Polymers

door Lee, Andrew M., Rojek, Jillian M., Gundersen, Anette, Ströher, Ute, Juteau, Jean-Marc, Vaillant, Andrew, Kunz, Stefan
Gepubliceerd in 2007

Inhibition of hepatitis B viral entry by nucleic acid polymers in HepaRG cells and primary human hepatocytes

door Guillot, Clément, Martel, Nora, Berby, Françoise, Bordes, Isabelle, Hantz, Olivier, Blanchet, Matthieu, Sureau, Camille, Vaillant, Andrew, Chemin, Isabelle
Gepubliceerd in PLoS One (2017)

Amphipathic DNA Polymers Exhibit Antiherpetic Activity In Vitro and In Vivo

door Bernstein, David I., Goyette, Nathalie, Cardin, Rhonda, Kern, Earl R., Boivin, Guy, Ireland, James, Juteau, Jean-Marc, Vaillant, Andrew
Gepubliceerd in 2008

Nucleic Acid Polymers with Accelerated Plasma and Tissue Clearance for Chronic Hepatitis B Therapy

door Roehl, Ingo, Seiffert, Stephan, Brikh, Celia, Quinet, Jonathan, Jamard, Catherine, Dorfler, Nadine, Lockridge, Jennifer A., Cova, Lucyna, Vaillant, Andrew
Gepubliceerd in Mol Ther Nucleic Acids (2017)

Amphipathic DNA polymers exhibit antiviral activity against systemic Murine Cytomegalovirus infection

door Cardin, Rhonda D, Bravo, Fernando J, Sewell, Andrea P, Cummins, James, Flamand, Louis, Juteau, Jean-Marc, Bernstein, David I, Vaillant, Andrew
Gepubliceerd in 2009

Potent Antiscrapie Activities of Degenerate Phosphorothioate Oligonucleotides

door Kocisko, David A., Vaillant, Andrew, Lee, Kil Sun, Arnold, Kevin M., Bertholet, Nadine, Race, Richard E., Olsen, Emily A., Juteau, Jean-Marc, Caughey, Byron
Gepubliceerd in 2006

Activity of nucleic acid polymers in rodent models of HBV infection

door Schöneweis, Katrin, Motter, Neil, Roppert, Pia L., Lu, Mengji, Wang, Baoju, Roehl, Ingo, Glebe, Dieter, Yang, Dongliang, Morrey, John D., Roggendorf, Michael, Vaillant, Andrew
Gepubliceerd in Antiviral Res (2017)

Amphipathic DNA Polymers Inhibit Hepatitis C Virus Infection by Blocking Viral Entry

door MATSUMURA, TAKUYA, HU, ZONGYI, KATO, TAKANOBU, DREUX, MARLENE, ZHANG, YONG–YUAN, IMAMURA, MICHIO, HIRAGA, NOBUHIKO, JUTEAU, JEAN–MARC, COSSET, FRANCOIS–LOIC, CHAYAMA, KAZUAKI, VAILLANT, ANDREW, LIANG, T. JAKE
Gepubliceerd in 2009

Modelling hepatitis D virus RNA and HBsAg dynamics during nucleic acid polymer monotherapy suggest rapid turnover of HBsAg

door Shekhtman, Louis, Cotler, Scott J., Hershkovich, Leeor, Uprichard, Susan L., Bazinet, Michel, Pantea, Victor, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Krawczyk, Adalbert, Dittmer, Ulf, Vaillant, Andrew, Dahari, Harel
Gepubliceerd in Sci Rep (2020)

Therapeutic Antiviral Effect of the Nucleic Acid Polymer REP 2055 against Persistent Duck Hepatitis B Virus Infection

door Noordeen, Faseeha, Scougall, Catherine A., Grosse, Arend, Qiao, Qiao, Ajilian, Behzad B., Reaiche-Miller, Georget, Finnie, John, Werner, Melanie, Broering, Ruth, Schlaak, Joerg F., Vaillant, Andrew, Jilbert, Allison R.
Gepubliceerd in PLoS One (2015)

Persistent Control of Hepatitis B Virus and Hepatitis Delta Virus Infection Following REP 2139‐Ca and Pegylated Interferon Therapy in Chronic Hepatitis B Virus/Hepatitis Delta Viru...

door Bazinet, Michel, Pântea, Victor, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Anderson, Mark, Gersch, Jeff, Holzmayer, Vera, Elsner, Carina, Krawczyk, Adalbert, Kuhns, Mary C., Cloherty, Gavin, Dittmer, Ulf, Vaillant, Andrew
Gepubliceerd in Hepatol Commun (2020)